histology of nerves and tissues

Question 1

how are myofibres arranged in skeletal muscle

Answer 1

in groups of fascicles sepereated by connective tissue

Question 2

which connective tissues are in skeletal muscle

Answer 2

epimysium
perimysium
endomysium

Question 3

what does basement membrane do

Answer 3

surrounds individual myofibres
collagen, glycoproteins and proteoglycans
roles in tensile strength, regeneration and development

Question 4

what is each muscle fibre innervated by

Answer 4

by one nerve
with cell bodies in anterior horn of spinal cord or brain stem
one neurone innervates multiple muscle fibres - motor unit

Question 5

what happens at neuromuscular junction

Answer 5

synapse - rapid transmission of depolarising impulse
acetylcholine - binds post synaptic AChR

Question 6

how to study skeletal muscle histology

Answer 6

by muscle biopsy
- requires the use of frozen sections and good orientation

EM

molecular tests

Question 7

what is proprioception

Answer 7

the sense that lets us perceive the location, movement, and action of parts of the body

Question 8

2 muscle fibre types

Answer 8

slow twitch

fast twitch

Question 9

what are fast twitch muscle fibres

Answer 9

they fatigue rapidly but generate a large peak of muscle tension