Histology of Lung

Question 1

Acute Bronchitis

Answer 1

Neutrophils in airway and walls

Question 2

Chronic Bronchitis

Answer 2

Squamous Metaplasia, Mucus gland hypertrophy, Chronic inflammation in walls

Question 3

Bronchiectasis

Answer 3

Compare airway size to associated pulmonary artery

Question 4

Asthma

Answer 4

Thick sub-basal lamina, eosinophilic inflammation (fewer in treated patients), mucus hyper-secretion, smooth muscle hyperplasia (from frequent constriction)

Question 5

Follicular Bronchiolitis

Answer 5

Germinal Centers

Question 6

Obliterative/Constrictive Bronchiolitis

Answer 6

inflammation & fibrosis causes scarring of airway closed (between mucosa and smooth muscle)

Question 7

Granulomatous Bronchiolitis

Answer 7

Histiocytes and giant cells

Necrotic attracts neutrophils

Question 8

Pneumonia

Answer 8

Neutrophils fill airspaces

Question 9

Eosinophilic Pneumonia

Answer 9

Usually from reaction (drugs)

Responds to steroids

Question 10

Organizing Pneumonia

Answer 10

Fibroblast plugs in airways, responds to steroids

Question 11

Diffuse Alveolar Damage

Answer 11

Hyaline Membranes (pink ribbons) in airspaces, thickened septa
Seen in ARDS

Question 12

Emphysema

Answer 12

enlarged airspaces, broken septa, sub-pleural blebs

Question 13

Smoking vs. Alpha-1-Antitrypsin Emphysema

Answer 13

Smoking worse in upper lobes

Alpha-1 is similar throughout

Question 14

Respiratory Bronchioloitis

Answer 14

Pigmented macrophages in airspaces, usually caused by smoking

Question 15

Desquamative Interstitial Pneumonia

Answer 15

Pigmented macrophages in airspaces