Histology- MSK Flashcards

1
Q

What types of muscle are there?

A

Smooth visceral, voluntary skeletal muscles, cardiac and other contractile cells like pericytes

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2
Q

What form muscels cells?

A

Myoblasts fuse to form a syncytium muscle fibres form to make fascicles and then form muscles

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3
Q

Why are skeletal muscles multimucleat?

A

They form from many myoblasts

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4
Q

What organelles are there in skeletal muscles?

A

There are cell membranes nuclei contractile proteins mant mitochondria sarcoplasmic reticulum and glycogen rich cytoplasm

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5
Q

What do muscle fibres look like on histology?

A

They have striated muscle elongated fibres multimucleat muclei at the edge of the fibres

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6
Q

What causes striation in the muscle fibres?

A

Striated muscle has myofibrels that are in register

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7
Q

What senses tension in the muscle?

A

Intrafusal muscle fibres with gamma efferent nerve fibres they detect stretch and tension

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8
Q

What are the connective tissues in muscle?

A

Endomysium between fibres, groups of fibres are bound together by perimysium and enpimysium which binds together fasicles

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9
Q

What are sharpey’s fibres?

A

They are the way that skeletal muscle is connected too collagen of bone they are bundles of collagen usualy over a large area

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10
Q

What are sharpey’s fibres?

A

They are the way that skeletal muscle is connected too collagen of bone they are bundles of collagen usually over a large area

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11
Q

Which cells are in bones or form bones?

A

Osteoprogenitor cells, osteoblasts, osteocytes an osteoclasts

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12
Q

What forms osteoblasts ans osteoclasts?

A

embryonec mesenchyme osteoprogenitor cells osteoclasts are from haemopoetic precursors

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13
Q

What corms osteocytes?

A

When osteoblasts become trapped in the bone

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14
Q

What connects osteocytes?

A

Canaliculi

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15
Q

What is osteoid?

A

Unmineralised bone

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16
Q

What are osteoclasts derived from?

A

from blood monocytes

17
Q

How many nuclei do osteoclasts have?

A

many

18
Q

What is the name for a crevace on the surface of bone?

A

Howship’s lacunae

19
Q

What is osteoclast activity linked to?

A

osteoblast Rank Ligand

20
Q

What is secondary bone?

A

Lamella bone formed slowly can often be made in seccondary osteon

21
Q

What is a haversian cannal?

A

The small part in secondary bone where blood vessels are

22
Q

What is intramembranous bone?

A

Bone that is formed from flat bones of the skull joining to form new bone

23
Q

What is endochondrial bone?

A

This is how most bone is made with a cartilage formation that becomes mineralised

24
Q

What are the cell types of synovium?

A

Type A- Phagocytic and Type B- Rich in rER

25
Q

What is synovium like?

A

1-4 layers of cells richly vascular and highly innervated