Histology Lab-Intestine

Question 1

Identify the labeled regions below

Answer 1

1) Stomach 2) Duodenum 3) Pyloric sphincter

Question 2

Identify the labeled regions shown below

Answer 2

1) Pancreas 2) Pancreatic duct 3) Muscularis externa 4) Serosa or Adventitia 5) Mucosa (note villi and intestinal crypts) 6) Brunner’s submucosal glands

Question 3

Identify the labeled regions shown below

Answer 3

1) Mucosal absorptive and goblet cells 2) Intestinal crypts 3) Muscularis mucosae 4) Brunner’s submucosal glands 5) Muscularis externa

Question 4

Identify the different structures indicated below

Answer 4

1) Absorptive cells (note brush border) 2) Goblet cells 3) Lymphocytes 4) Nucleus of goblet cell 5) Lamina propria with capillaries and lacteals

Question 5

Identify the different structures indicated below.

Answer 5

Note the villi and absence of submucosal glands, this is the jejunum 1) Muscularis externa 2) Serosa 3) Mucosa with villi and intestinal crypts 4) Lymphoid nodule

Question 6

What structure is indicated below?

Answer 6

Paneth cell. Note the large red granules oriented towards the lumen.

Question 7

What structure is indicated below?

Answer 7

Enteroendocrine cell. Note the red granules oriented towards the basal aspect of the cell.

Question 8

Identify the structures indicated in the image below.

Answer 8

Note the Peyer’s patches, indicating that we are in the ileum. 1) Mucosa with villi and intestinal crypts 2) Serosa 3) Muscularis externa 4) Submucosal Peyer’s patch

Question 9

Clusters of what type of cell might you find over Peyer’s patches?

Answer 9

M cells

Question 10

What structure is indicated below?

Answer 10

Note the PAS-staining Peyer’s patches in addition to goblet cells and surface mucous. This tells you that you are in the ileum. That means the fold indicated in the image is plicae circularis.

Question 11

What cells are indicated in the image below?

Answer 11

1) Surface mucous cell of the stomach 2) Goblet cell of the intestine. Note how the stomach side of the gastroduodenal junction is PAS positive for every cell lining the stomach and on the intestine side only goblet cells are PAS positive.

Question 12

Identify the structures indicated in the image below:

Answer 12

This is the appendix 1) Serosa 2) Lymphatic nodules 3) Mucosa w/ shallow crypts w/lymphoid cells 4) Muscularis externa 5) Epiploic appendage

Question 13

Identify the labeled structures below:

Answer 13

This is the colon. Note the lack of villi and presence of intestinal crypts w/a longitudinal muscle layer of 3 bundles. 1) Muscularis externa 2) Tenia coli 3) Mucosa: note lack of villi 4) Submocosa w/ adipocytes

Question 14

Where is this slice taken from?

Answer 14

Colon.