Histology: Histological Structure of Muscle Flashcards
What does the parenchyma of an organ consist of?
the tissue which:
- conducts the specific function of the organ
- usually comprises the bulk of the organ
What is the stroma of an organ?
Everything apart from the parenchyma:
- connective tissue,
- blood vessels,
- nerves,
- ducts.
What is the parenchyma of skeletal tissue?
muscle tissue
What is the stroma of skeletal muscle?
connective tissue, blood vessels and nerves.
What are “parenchyma” and “stroma” terms applicable to?
parenchymal organs only! cannot be applied to tuberal organs!
How can one classify tuberal organs?
lumen (inside)
When does differentiation continue in skeletal muscles?
after the fibers have been formed and have reached a functional state.
How can muscle fibers be differentiated?
- red muscle
- mixed muscle
- white muscle
What is the difference between red and white muscles?
- same structural composition
- different proportions of myoglobin and mitochondria
How are vertebral skeletal muscle fibers differentiated?
into red (type 1, slow twitch), and white (type 2) muscles
Explain type 1 muscle fibers? What is their different name?
type 1 = slow twitch = red muscle
- dense with capillaries
- rich in mitochondria
- rich in myoglobin
(giving the muscle its red colour)
- relatively more sarcoplasm
Explain type 2 muscle fibers? What is their different name?
type 2 = fast twitch = white muscle
- less dense in mitochondria
- less dense in myoglobin
What types of fibers develop high myoglobin concentrations?
fibers specialised for aerobic metabolism
How do type 1 fibers contract? speed? force required? fatigue?
slow twitch fibers contract for long periods of time, with little force. fatigue very slowly/never.
Which type of fibers have limited contractions?
type 1 fibers, slow twitch
State an example of slow twitch fibers?
- in the mouth
- breathing
work for an unlimited time
How do type 2 fibers contract? fatigue? speed? force required?
fast twitch fibers:
- contract quickly and powerfully,
- fatigue very rapidly
- sustain only short anaerobic bursts of activity before muscle contraction becomes painful
Why do small animals have pale coloured flesh?
major fast muscle type (type 2) predominates.
What is an important feature of muscle fibers?
transdifferentiation.
red muscle tissue <–> white muscle tissue
What is a “mixed muscle”?
a type of muscle which contains both white and red muscle fibers
most muscles in the organism
What are the names of the different connective tissue layers covering muscle?
1) endomysium
2) perimysium
3) epimysium
What holds together skeletal muscle?
connective tissue
What is the function of connective tissue in skeletal muscle fibers?
hold together the skeletal muscle fibers
What is the function of the endomysium?
surround individual fibers (cells not myofibril).
surrounding the group of tubes