Histology

Question 1

In what states will you see hypersegented neutrophils?

Answer 1

Vit B12 and folate deficiencies (or orotic aciduria caused by UMPS deficiency)(megaloblastic anemia).

Question 2

What cytokine activates macrophages?

Answer 2

gamma-interferon

Question 3

Cell surface marker for macrophages?

Answer 3

CD14

Question 4

There will be an unusually high blood level of this WBC in collagen vascular disease.

Answer 4

Eosinophil

Question 5

This drug prevents mast cell degranulation.

Answer 5

Cromolyn sodium

Antihistamines act by inhibiting histamine receptors or production from histidine.

Question 6

What are Langerhans cells?

Answer 6

Dendritic cells on skin

Question 7

2 main cell surface markers of B-cells.

Answer 7

CD19, CD20

Question 8

Multiple myeloma is neoplasm of which WBC?

Answer 8

Plasma cells

Question 9

What cell surfce marker is common to all T-cells?

Answer 9

CD3

Question 10

What is the co-stimulatory molecule on T-cells?

Answer 10

CD28

Question 11

What receptor does EBV use to bind to B-lymphocytes?

Answer 11

CD21