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Anatomy Test 4 > histology 2- cartilage > Flashcards

histology 2- cartilage Flashcards

1
Q

origin of chondroblast

A

mesenchyme cells

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2
Q

cartilage composition

A

cells and ECM

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3
Q

cartilage

A

composition
perichondrium
avascular

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4
Q

cartilage cells

A

chondroblast

chondocytes

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5
Q

chondroblast

A

on outside surface of tissue, produce ECM, not completely surrounded by ECM yet

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6
Q

chondrocytes

A

also produce matrix, also maintain it. on inside of cartilage, completely surrounded by ECM

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7
Q

when do chondroblast turn into chondrocytes

A

when ECM completely surrounds the cell

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8
Q

what is space called that cells sit inside after surrounded by ECM

A

lacunae

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9
Q

characteristics of cartilage ECM

A
  1. 95% water
  2. Rich in GAG’s and proteoglycans
  3. allows for withstanding forces, resilent
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10
Q

dense CT covering most cartilage

A

perichondrium

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11
Q

perichondrium

A

contains blood vessels, nerves, chondrogenic cells, type 1 cartilage, important in growth and maintenance of cartilage

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12
Q

chondrogenic cells

A

found in perichondrium, produce chondroblast

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13
Q

what limits diffusion thus limiting growth in cartilage

A

avascular

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14
Q

2 mechanisms of growth

A

appositional growth

interstital growth

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15
Q

appositional growth

A

growth by additional to existing surface. generation of new chondroblast, adding in addiontal ECM

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16
Q

interstital growth

A

growth by internal expansion. proliferation of chondrocytes and formation of isogenous groups. have to start producing ECM in between cells which makes tissue grow

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17
Q

isogenous groups

A

cluster of chondrocytes in lacunae, undergo mitosis

18
Q

3 types of cartilage

A
  1. hyalin
  2. elastic
  3. fibrocartilage
19
Q

hyalin cartilage ECM composition

A

75% water, proteoglycans, Hyaluaric acid, type 2 collagen!

20
Q

what is most common cartilage in human body

A

hyalin cartilage

21
Q

location of hyalin cartilage

A

nose, larynx, tracheal cartialge, fetal bone models, articular surfaces

22
Q

does hyalin have perichondrium

A

yes

23
Q

appearance of hyalin cartilage

A

fresh discect- bluish-white and translucent

matrix is basophilic- can’t see collagen type 2 fibers

24
Q

shape of chondrocytes compared to chondroblast

A

cytes are more rounded.

25
Q

hyalin cartilage is more ____philic

A

basophilic

26
Q

perichondrium is more _____philic

A

eosinphilic

27
Q

what indicates growing cartilage, newly synthesized cells

A

isogenous groups

28
Q

right around isogenous groups stain _____

A

darker

29
Q

what is stained lighter around isogenous groups, darker?

A

interterritorial matrix, territorial matrix.

30
Q

interterritorial matrix has lots of ______

A

collagen fibers

31
Q

territorial ECM richer in what

A

GAG’s, not as much collagen

32
Q

what binds to GAG’s to give territorial darker color

A

hematoxylin

33
Q

elastic cartilage ECM composition

A

essentially the same as hyalin cartilage. type 2 cartilage plus elastic fibers.

34
Q

location of elastic cartilage

A

auricle, auditory tube, auditory canal, epiglottis

35
Q

appearance of elastic cartilage newly dissection

A

yellow in color cuz of elastic cartilage

36
Q

how to differentiate elastic cartilage

A

higher ratio of chondroytes to matrix. (ALOT MORE CELLS)

fewer cells per isogenous groups (2-3)

37
Q

fibrocartilage ECM composition

A

type 1 collagen

less proteoglycans than other other cartilages.

38
Q

location of fibrocartilage

A

intervertebral disc
pubic symphysis
major tendon-bone anchorages

39
Q

does fibrocartilage have perichondrium

A

no

40
Q

appearance of fibrocartilage

A

tissue intermediates between dense regular connective tissue and hyalin cartilage.
chondrocytes arragned in long rows separated by coarse collage fibers.

41
Q

matrix of fibrocartilage is more ______

A

acidophilic

42
Q

what does lots of type 1 collagen help with

A

high tensile strength, under goes lots of pressure. can handle lots of pressures

Anatomy Test 4 (11 decks)

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