Histological Change and Disease

Question 1

Mesothelioma

Answer 1

simple squamous epithelium, mesothelium
changes: 
fragmented basement membrane
tumor cells (with microvilli)
= metastisis

Question 2

Atherosclerosis

Answer 2

simple squamous epithelium, endothelium
changes:
foam macrophages 
fragmented internal elastic lamina
fat deposits
= vascular occlusion/stroke

Question 3

hyperthyroidism

Answer 3

simple cuboidal epithelium, thyroid
changes:
active columnar cells
= Graves disease

(can also have hypothyroidism)

Question 4

celiac disease

Answer 4

simple columnar epithelium, sm intestine
changes:
loss of mmicrovilli
disrupted terminal web
lymphocyte in lamina propria
intraepithelial lymphocyte
= malabsorbtion, anemia, bone disease, cancer

Question 5

bronchitis

Answer 5

pseudrostratified columnar epithelium, trachea
changes:
loss of cilia
mucus
few basal bodies, hyperplastic columnar cells
squamous cells
inflammatory cells in CT

Question 6

barett syndrome

Answer 6

stratified squamous epithelium (nonkeratinized)
changes:
metaplastic columnar cells
goblet cells
inflammatory cells
= gastroesophageal reflux