His Moans & Her Moans

Question 1

What is the male & female target tissue for FSH?

Answer 1

male: testis (Sertoli cells: S.cell function)

female: ovary (Granulosa cells: follicular development & E2 synth)

Question 2

What is the male & female target tissue for LH?

Answer 2

Male: testis {interstitial cells of Leydig: stim T2 production}

​Female: ovary {theca interna & luteal cells: stim ovulation, CL form’n, & P4 secretion}

Question 3

What is the male & female target tissue for prolactin?

Answer 3

male: testis & brain {can induce maternal behavior in males & females}

female: mammary cells & CL (in some species)
{lactation, maternal behavior, & CL function}

Question 4

What is the male & female target tissue for GnRH?

Answer 4

Male & Female: anterior pituitary, gonadotroph cells
{release of LH & FSH from anterior pituitary}

Question 5

What is the male & female target tissue for oxytocin (OT)?

Answer 5

Male: sm.muscle of the epididymal tail, ductus deferens, & ampulla
{PGF-2a synthesis & pre-ejaculatory movement of spermatozoa}

Female: myometrium, endometrium, & myoepithelial cells of mammary gland
{uterine motility, promotes uterine PGF-2a synth, milk ejection}

Question 6

What is the male & female target tissue for Progesterone (P4)?

Answer 6

male: NONE.

female: myo-& endo-metrium, mammary gland, hypothalamus
{endometrial secretion, inhibits GnRH release, inhibits repro behavior,
promotes maintenance of pregnancy}

Question 7

What is the male & female target tissue for estradiol (E2)?

Answer 7

male: brain; inhibits long bone growth {sexual behavior}

female: hypothalamus, entire repro tract, & mammary gland {sexual behavior, GnRH, elevated secretory activity of entire tract, enhanced uterine motility}

Question 8

What is the male & female target tissue for testosterone?

Answer 8

Male: accessory sex glands, tunica dartos of scrotum, seminiferous epithelium, skeletal muscle
{anabolic growth, promotes spermatogenesis, promotes secretion of accessory sex glands}

Female: brain, skeletal muscle, granulosa cells
{substrate for E2 synth; abnormal masculinization}

Question 9

What is the male & female target tissue for inhibin?

Answer 9

male & female: gonadotrophs of anterior pituitary
{inhibits FSH secretion}

Question 10

What is the male & female target tissue for activin?

Answer 10

male & female: gonadotrophs of anterior pituitary {stimulates FSH secretion}

Question 11

What is the male & female target tissue for PGF-2a?

Answer 11

male: epididymis {affects metabolic activity of spermatozoa, causes epididymal contractions}

female: CL, myometrium, ovulatory follicles
{l**uteolysis, promotes uterine tone & contraction, ovulation}

Question 12

What hormones do granulosa cells produce?

Answer 12

Inhibin, activin, E2 {female}

Question 13

What hormones does the placenta produce?

Answer 13

E2, P4, placenta lactogen

Question 14

Which 3 reproductive hormones are sourced in the anterior pituitary gland?

Answer 14

1. FSH
   {gonadotroph cells}
2. LH
   {gonadotroph cells}
3. Prolactin
   {lactotroph cells}

Question 15

Where is E2 sourced from?

Answer 15

• *Granulosa cells** of follicle,
• *Placenta**,

& *Sertoli cells of testis in males

Question 16

Where is PGF-2alpha sourced from?

Answer 16

Uterine endometrium,
vesicular glands

Question 17

Where is testosterone sourced from?

Answer 17

Male: interstitial cells of Leydig,

​Female: theca interna cells

Question 18

What is the male & female target tissue for Prostaglandin E2 (PGE2)?

Answer 18

Male: NONE

Female: corpus luteum, oviduct {ovulation; stims CL secretion of P4}

Question 19

Where is PGE2 sourced from?

Answer 19

ovaries,
uterus,
embryonic membranes