hippuran and MAG3 Flashcards

1
Q

renal imaging agents assess

A

renal function using physiological properties

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2
Q

what % is secreted via tubular secretion for hippuran

A

80% active

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3
Q

% excreted glomerular filtration for hippuran

A

20% passive

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4
Q

Hippuran aka

A

ortho iodohippurate

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5
Q

hippuran is labeled with what two isotopes

A

I123 and I131

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6
Q

hippuran is secreted mostly how

A

actively from blood through nephron

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7
Q

hippuran blood clearence on first pass

A

70%

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8
Q

secretion from vasculature&raquo_space;.

A

tubules in nephron indicate kidney function

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9
Q

MAG3 stands for

A

Tc-MercaptoAcetylGlyclGlyclGlyclGlycine

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10
Q

what was mag 3 made for

A

assesing renal f(x) with something Tc based

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11
Q

How is mag3 mainly secreted

A

via tubular secretion

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12
Q

mag3 tubular secretion %

A

90% active

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13
Q

mag 3 glomerular filtration %

A

8-10% passive

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14
Q

other small percent filtered via

A

billiary system

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15
Q

why is less than 70% blood clearnece on first pass

A

bc substantial protein binding in the blood

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16
Q

what 3 things come in mag 3 kit

A

SnCl2, Tartaric acid, betatide which is a precursor to Mag3

17
Q

how id mag 3 made

A

tc is reduced by SnCl2 and binds tartrate to form intermediate labeled compound» excess Sn+2 eliminated by intro of oxygen in the form of filtered room air»> w/in 5 min of adding Tc heat in water bath for 10 min» heating will cause reduced Tc atom exchanged from tartrate to betatide molecule which is core of MAG3 molecule

18
Q

mag3 common name

A

mertiatide by mallinckodt

19
Q

mag3 expires when

A

6 hours after prep

20
Q

keep mag3 away from

A

light