hippuran and MAG3 Flashcards
renal imaging agents assess
renal function using physiological properties
what % is secreted via tubular secretion for hippuran
80% active
% excreted glomerular filtration for hippuran
20% passive
Hippuran aka
ortho iodohippurate
hippuran is labeled with what two isotopes
I123 and I131
hippuran is secreted mostly how
actively from blood through nephron
hippuran blood clearence on first pass
70%
secretion from vasculature»_space;.
tubules in nephron indicate kidney function
MAG3 stands for
Tc-MercaptoAcetylGlyclGlyclGlyclGlycine
what was mag 3 made for
assesing renal f(x) with something Tc based
How is mag3 mainly secreted
via tubular secretion
mag3 tubular secretion %
90% active
mag 3 glomerular filtration %
8-10% passive
other small percent filtered via
billiary system
why is less than 70% blood clearnece on first pass
bc substantial protein binding in the blood
what 3 things come in mag 3 kit
SnCl2, Tartaric acid, betatide which is a precursor to Mag3
how id mag 3 made
tc is reduced by SnCl2 and binds tartrate to form intermediate labeled compound» excess Sn+2 eliminated by intro of oxygen in the form of filtered room air»> w/in 5 min of adding Tc heat in water bath for 10 min» heating will cause reduced Tc atom exchanged from tartrate to betatide molecule which is core of MAG3 molecule
mag3 common name
mertiatide by mallinckodt
mag3 expires when
6 hours after prep
keep mag3 away from
light
