brain (ECD) Flashcards
1
Q
Tc ECD aka
A
Tc EthylCisteinateDimer (neurolite/bicisate)
2
Q
what is ecd
A
a lipid soluble
3
Q
how does ecd cross BBB
A
diffuses into tissue and is metabolized into polar compound that can not be rediffused out
4
Q
brain uptake of ecd
A
5-6%
5
Q
T/F: slow washout and no redisprution
A
true
6
Q
minimal ____ uptake
A
lung
7
Q
biliary upatke/ excretion %
A
10%
8
Q
renal excretion %
A
60%
9
Q
sn reduces
A
tc
10
Q
how many vials
A
2 A and B
11
Q
whats in the vials
A
A- EDTA and B=phosphate buffer
12
Q
how does DMSA kit work
A
add 2 mL of TcO4 to B and dissolve A with 3 mL of normal saline and then take 1 mL of A and add to B and the Tc biinds to the EDTA and then incubates for 15 mi while transhleation occurs and transfers Tc to ECD
13
Q
exp in
A
6 hrs
