brain (HMPAO)

Question 1

brain scanning RPS work by

Answer 1

diffusing across BBB and the BBB prevents lg polar molecules from leaving vasculature and entering the cerebral tissue

Question 2

HMPAO aka

Answer 2

exazetamine

Question 3

how does HMPAO work

Answer 3

diffuses through BBB into cerebral tissue after 1 min post inj and after 2 min small perent gets out but no change after 24 hr

Question 4

max upatke % in brain is

Answer 4

4-5 % after 1 min

Question 5

what reduces Sn2+

Answer 5

Sn reduces TC

Question 6

why is the old formula exp after 30 min

Answer 6

because the rapid conversion of primarily labeled lipophyllic compound is in excess

Question 7

how do you stabilize HMPAO (stop the converison of primary lipophyllic compound)

Answer 7

methylene blue solution to retain 80% purity and exp after 4 hours

Question 8

HMPAO filtered through what size

Answer 8

0.45 um bc methylene blue solution may contain particulates

Question 9

Tc eluted w/in how many hours

Answer 9

24 but pref 30 min