hip Flashcards
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012. - DI predicted how many (all DI > 0.35) would get OA due to dysplasia?
Whereas OFA @ 2 yrs predicted what %?
Radiographic and Histopath
- DI predicted all of them (DI > 0.35) and 98% over all for both radiographic and histo.
Whereas OFA @ 2 yrs predicted less than half (45% negative predictive value for rad OA and 8% for histo)
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012
OFA @ 2 yrs had a negative predictive value of __% for radiographic end of life OA
OFA @ 2 yrs had a negative predictive value of 45% for radiographic end of life OA
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012
___% of dogs who scored “normal” OFA @ 2 yrs went on to develop radiographic OA
55% of dogs who scored “normal” OFA @ 2 yrs went on to develop radiographic OA
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012
Of the 55% of dogs who scored “normal” OFA @ 2 yrs and went on to develop radiographic OA, __% of these dogs had radiographic OA at end of life
- 55% of dogs who scored “normal” @ 2 yrs went on to develop radiographic OA- (67% of these dogs had radiographic OA at end of life)
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012
OFA is profoundly influenced by ___________ factors
OFA is profoundly influenced by environmental factors
Smith; Chronology of Hip Dysplasia Development in a Cohort of 48 Labrador Retrievers Followed for Life. Vet Surg. 2012
Was DI shown to be influenced by environmental factors in this study?
Was their a diff in DI between the diet fed and control fed dogs?
no, because DI was only measured at 2 years,
DI was the same between the diet fed and control fed dogs
Krontveit Housing- and exercise-related risk factors associated with the development of hip dysplasia as determined by radiographic evaluation in a prospective cohort of Newfoundlands, Labrador Retrievers, Leonbergers, and Irish Wolfhounds in Norway. Am J Vet Res. 2012 ; In this study, dogs-501 dogs radiographed at ___ or ___ months
12 or 18 months
Krontveit Housing- and exercise-related risk factors associated with the development of hip dysplasia as determined by radiographic evaluation in a prospective cohort of Newfoundlands, Labrador Retrievers, Leonbergers, and Irish Wolfhounds in Norway. Am J Vet Res. 2012; Their conclusions regarding pups
conclusions: pups walking on stairs from birth to 3 months of age = predisposed to hip dysplasia
Youkhanna; Bone Resorption Markers and Dual-Energy X-Ray Absorptiometry in Dogs with Avascular Necrosis, Degenerative Joint Disease, and Trauma of the Coxofemoral Joint. Vet Surg. 2012
NTx = N-teleopeptide from _________ breakdown is a biomarker for ____ _____ in humans
collagen; biomarker for bone resorption in humans
Youkhanna; Bone Resorption Markers and Dual-Energy X-Ray Absorptiometry in Dogs with Avascular Necrosis, Degenerative Joint Disease, and Trauma of the Coxofemoral Joint. Vet Surg. 2012; little dogs with avascular necrosis of femoral head have incr. serum _____, decr. ____, and n urine ____
little dogs with avascular necrosis of femoral head have incr. serum NTx, decr. BMD, and n urine NTx
Youkhanna; Bone Resorption Markers and Dual-Energy X-Ray Absorptiometry in Dogs with Avascular Necrosis, Degenerative Joint Disease, and Trauma of the Coxofemoral Joint. Vet Surg. 2012; large dogs with DJD had no change in ____ of their femoral heads (no conclusions re NTx)
large dogs with DJD had no change in BMD of their femoral heads (no conclusions re NTx)
Youkhanna; Bone Resorption Markers and Dual-Energy X-Ray Absorptiometry in Dogs with Avascular Necrosis, Degenerative Joint Disease, and Trauma of the Coxofemoral Joint. Vet Surg. 2012; in general, how does serum NTx correlate with BMD? How did urine fair?
in general, serum NTx correlates (inversely) with BMD, but urine NTx is useless
Youkhanna; Bone Resorption Markers and Dual-Energy X-Ray Absorptiometry in Dogs with Avascular Necrosis, Degenerative Joint Disease, and Trauma of the Coxofemoral Joint. Vet Surg. 2012- in general, small dogs have _____ NTx and _____ BMD than large dogs
- in general, small dogs have less NTx and lower BMD than large dogs
Martins; Morphometric assessment of the hip joint in the Estrela Mountain Dog breed. VCOT 2012- describes a novel modified measurement of what hip angle?
acetabular angle of retroversion
Martins; Morphometric
assessment of the hip joint in the Estrela Mountain Dog breed. VCOT 2012– femoral neck and acetabular morphometric measurements not comparable btwn diff ____and ____ _____
femoral neck and acetabular morphometric measurements not comparable btwn diff ages and dz states
Martins; Morphometric assessment of the hip joint in the Estrela Mountain Dog breed. VCOT 2012- Conclusion: What 3 things did not seem to be a predisposing factor for CHD?
femoral anteversion, inclination, and neck length didn’t seem to be predisposing factors for HD
Karbe; Corgi Hips
All Corgi’s in the PennHIP database had DI >0.3, What was the mean DI?
0.66
If S-value is < __ mm, then no CHD
5
Kirkby. Review evidence medical management of CHD. Best evidence
available from Level II papers is for what medical treatment recommendation?
weight control
Kirkby. Review evidence medical management of CHD. Reasonable evidence exists for what other 2 medical txt recommendations?
PSGAG’s and mesenchymal stem cells
Kirkby. Review evidence medical management of CHD. Evidence for PT/hydrotherapy?
no good evidence
Kirkby. Review evidence medical management of CHD. Also noted “weak” evidence for what non-surgical therapy?
extracorporeal shock wave therapy
Case. Compare locking parallel screws to locking divergent screws vs. non-locking for experimentally induced rotational osteotomies in dogs. Which construct had less screw loosening?
Locking plate with parallel screws
Case. Compare locking parallel screws to locking divergent screws vs. non-locking for experimentally induced rotational osteotomies in dogs. Which construct had best yield load?
Locking plate with parallel screws