Hgb Composition

Question 1

GLOBIN

1. 1 GLOBIN unit = ___ polypeptide chains
   - _____: composed of 2 sets of 2 different polypeptide
   - ___ due to its quaternary structure
2. determines the type of hgb
   - synthesized in _____
3. the one we need to be able to synthesize polypeptide chain

Answer 1

1. 4 polypeptide chains
   - DIMEE
   - TETRAMER
2. GLOBIN CHAINS
   - SPECIFIC RIBOSOMES
3. GENES

Question 2

POLYPEPTIDE CHAINS OF THESE
1. Gower-1
2. Gower-2
3. Portland 1
4. Portland 2
5. HbA1
6. HbA2
7. HbF

Answer 2

1. 2 zeta; 2 epsilon
2. 2 alpha; 2 epsilon
3. 2 zeta; 2 ganma
4. 2 zeta; 2 beta
5. 2 alpha; 2 beta
6. 2 alpha; 2 delta
7. 2 alpha; 2 gamma

Question 3

_____: This is an inorganic iron group that assist in binding O2

1. each polypeptide chain = ___ heme group
2. Each 1 heme group =
   - 4 _____
   - 4 _____ (nitrogenous substance formed in mitochondrion)
3. 1 Rbc can bind ____ of oxygen since there are 4 heme groups
   4.1g of hgb = ___mL of oxygen
   - 600g of total hgb = ___mL of oxygen

Answer 3

HEME

1. 1 heme group
2. Each 1 heme group =
   - 4 ferrous iron
   - 4 protoporphyrin IX
3. 4molesof oxygen
   4.1.34ml
   - 800ml