HF BBs Flashcards

1
Q

What is the brand name of bisoprolol?

A

Zebeta

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2
Q

What is the initial dose of bisoprolol?

A

1.25 mg daily

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3
Q

What is the target dose of bisoprolol?

A

10 mg daily

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4
Q

What is the brand name of carvedilol?

A

Coreg, Coreg CR

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5
Q

What is the initial dose of coreg?

A

3.125 mg BID for two weeks

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6
Q

What is the target dose of coreg?

A
  • <85 kg: 25 mg BID
  • > 85 kg: 50 mg BID
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7
Q

What is the initial dose of coreg CR?

A

10 mg daily for two weeks

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8
Q

What is the target dose of coreg CR?

A

80 mg daily

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9
Q

What is the brand name of metoprolol CR/XL?

A

Toprol XL

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10
Q

What is the initial dose of metoprolol CR/XL?

A

12.5-25 mg daily

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11
Q

What is the target dose of metoprolol CR/XL?

A

200 mg daily

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12
Q

What is the dosing titration of BBs?

A
  • Double dose q2weeks and MONITOR closely vital s/sxs
  • Planned dose increases can be slowed if necessary to manage
  • AIM FOR TARGET DOSE in 8-12 wks or highest tolerated dose
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13
Q

What is the dose conversion between carvedilol and coreg CR?

A
  • 3.125 mg BID = 10 mg QD
  • 6.25 mg BID = 20 mg QD
  • 12.5 mg BID = 50 mg QD
  • 25 mg BID = 80 mg QD
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14
Q

What are the monitoring parameters of BBs?

A
  • BP (and sx hypotension), HR (1-2 wks)
  • Edema and fluid retention (1-2 wks)
  • Fatigue or weakness
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15
Q

What are the specifics to BP, sx hypotension, and HR monitoring of BB?

A
  • Sx hypotension, bradycardia, and dizziness are uncommon if slow titration (reduce dose 50% if necessary)
  • If hypotension only, reduce other drugs first
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16
Q

What are the specifics to edema and fluid retention monitoring of BB?

A
  • Risk is 1-2% (more than placebo) if stable, euvolemic pts are chosen
  • Intensify diuretic therapy
17
Q

What are the specifics to fatigue or weakness monitoring of BB?

A
  • Risk is 1-2% (more than placebo)
  • May resolve on own or may require decrease or d/c