(3.10) Pharmacology of anticonvulsant drugs & drugs to tx absence seizures Flashcards by Eli Lee | Brainscape

Q

What drug is in the succinimides class?

A

Ethosuximide (zarontin)?

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What is the MOA of ethosuximide (zarontin)?

A

Blocks T-type Ca channels (low threshold current) in thalamic neurons
T-type Ca channels are through to be involved in generating the rhythmic discharge of an absence attack

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

What are the toxicities of ethosuximide (zarontin)?

A

GI distress, sedation

How well did you know this?

1

Not at all

2

3

4

5

Perfectly