Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

My own Pharma > HF > Flashcards

HF Flashcards

1
Q

HF + fluid retention first line drug?

A

first Loop D. - Furosemide then ACEi or ARB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

HF + no fluid retention TOC?

A

First ARNi + ARB
then beta-blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DOC emergency HTN pregnancy

A

First Labetalol then Methyl-dopa then Hydralazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

If after ARNi and ARB, Beta blockers also fail in HF, what’s the next step?

A

Mineralocorticoid Receptor blocker - Spironolactone (alternate)
SGLT2i - Gliflozins - antidiabetic
Vericiguat - Guanyl cyclase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Last choice drugs in HF?

A

Ivabradine (HR>70)
Digoxin (symptomatic)
Both used for persistent symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Best drugs for chronic HF?

A

ARNI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which anti-diabetic drug is used for HF?

A

Gliflozins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drugs that relieve congestion in HF?

A

Diuretics (loop) - Furosemide
Natriuretic - Nesiritide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drugs that Increase pumping action in HF pts?

A

Dopamine and Dobutamine
Ionotropic agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

ARNI is?

A

ARB + Neprilysin inhibitor
(it’s an enzyme that breaks ANP AND BNP, but if they don’t break ANP BNP increase which show diuretic effect)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drugs that inhibit remodeling and increase survival in HF pts?

A

Beta blockers
ARB
ACEi
Pot sparing diuretics/aldosterone antagonist
SGLT-2 inhibitors - Gliflozin
Hydralazine + Nitrate
Ivabradine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Action of Hydralazine + Nitrate?

A

Hydralazine is Atrial dilator
Nitrate is Venous dilator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ivabradine specifications and use?

A

Causes bradycardia (use in HR>70) after beta blocker use
in HF pts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which drug uses funny channel inhibition for its function?

A

Ivabradine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Luminous phenomenon is S/E of which drug?

A

Ivabradine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

–pril which drugs?

A

ACEi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Example of ARBs used in ARNI-HF drug therapy?

A

Valsartan + Sacubitril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

beta-1 agonist used in shock + oliguria?

A

Dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

beta-1 agonist used in acute pump failure?

A

Dobutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

beta-1 agonist used in cardiogenic shock?

A

Nor-adrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

DOC digitalis drugs toxicity? (Digoxin and Digitoxin)

A

Lidocaine/Lignocaine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

DOC severe digitalis drugs toxicity?

A

Digibind
KCl last option

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Which drugs are indicated to be used in severe and refractory CHF?

A

PDE-3 inhibitors = increase C-AMP = dilates blood vessels (ionodilators)
eg:
Amrinone
Milrinone
Levosimendan - Ca sensitizer

24
Q

Which PDE inhibitor drug used in CHF is Ca sensitizer?

A

Levosimendan

25
Q

Which is the newer drug for CHF?

A

Omecamtiv - myosin activator

26
Q

Digoxin MOA?

A

Na-K-ATPase inhibitor (increase contractility - positive ionotrope) + Vago-mimetic (decrease HR - negative chronotropic)

27
Q

Why is Digoxin used for CHF?

A

Because it increases contractility and its positive ionotrope

28
Q

Why is Digoxin used for SVT?

A

Because it decreases HR and is negative chronotrope

29
Q

3 drugs for SVT?

A

Beta blocker
CCB
Digoxin

30
Q

SVT + HF DOC?

31
Q

Which site in myocardial cell digoxin bind to?

A

K (less K means more digoxin binding)

32
Q

Highest risk caused by Digoxin?

A

Arrythmia (MC ventricular)
Yellow vision - Xanthopsia

33
Q

Which arrythmia is NOT caused by Digoxin?

A

Atrial flutter

34
Q

Which arrythmia caused by digoxin is most characteristic?

A

SVT with AV block

35
Q

Name drugs that increase digitalis toxicity?

A

Verapamil
Diltiazem
Quinidine

36
Q

Name drugs that decrease digitalis toxicity?

A

Antacids
Sucralfate

37
Q

DOC WPW syndrome?

A

Flecainide/Procainamide

38
Q

DOC HOCM (hypertropic obstructive cardiomyopathy)?

A

Negative ionotrops = beta blockers

39
Q

C/I Digoxin

A

WPW Syndrome
Hypokalemia - will cause digoxin toxicity
HOCM
Partial AV block
MI
high output heart failure

40
Q

Which drug group is not safe to be given with Digoxin?

41
Q

PSVT DOC

42
Q

DOC Sinus bradycardia, mobitz type 1and first degree heart block

43
Q

TOC mobitz type 2 and complete heart block?

44
Q

Best anticonvulsant in Eclampsia

45
Q

Best antihypertesive in Eclampsia

46
Q

First sign of Mg toxicity?

A

Loss of deep tendon reflex

47
Q

DOC Mg and Ca toxicity

A

Calcium gluconate
10-10-10 rule

48
Q

Drug used for stress ECHO

A

Dobutamine

49
Q

DOC classical angina

A

Beta blockers

50
Q

Best antihypertesive in IHD

A

Beta-blockers

51
Q

Best drug for prinzmetal vasospastic angina and peripheral vascular disease?

A

CCBs (dipines) - vasodilation needed

52
Q

Which drugs are good in angina + diabetes?

A

FS Oxidase inhibitor - Ranolazine & Trimetazidine
Better Hb1Ac control

53
Q

DOC acute IHD attack

A

Nitroglycerine

54
Q

Drugs with high first pass, metabolism

A

Nitrates
Propranolol
Lignocaine

55
Q

Nitrates given by sublingual route are?

A

GTN and IDN (Sorbitrate - jeeb me rakho)

56
Q

In which spasms/colic patients Nitrates are not effective?

57
Q

Monday headaches address caused by?

A

Nitrates tolerance holidays

My own Pharma (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions