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Virology > Herpesviridae > Flashcards

Herpesviridae Flashcards

1
Q

What causes sudden death in chickens?

A
  1. Metabolic disease ( lactic acidosis)

2. Cardiac problems (breeding, stress)

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2
Q

What infectious agents are on the potential bioterrorism list?

A
  1. Avian influenza

2. IBDV

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3
Q

What are cause of swollen eye/conjunctivitis/systemic illness in wild finches?

A
  1. Mycoplasma gallisepticum
  2. Vitamin A deficiency
  3. Chlamydia psittaci
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4
Q

What are causes of house finch and goldfinch deaths?

A
  1. Pacheco’s herpesvirus
  2. Avian influenza
  3. Mycoplasma
  4. West Nile Virus-paramyxovirus
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5
Q

What is a latent infection?

A

Virus particles are always present in the animals and cannot find full virions in the body, but can find the viral genome hidden in the nucleus.

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6
Q

What is a recurrent infection?

A

The genome wakes up and makes new infectious virions.

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7
Q

Which of the following viruses have tissue tropism for respiratory system?

a. Feline calicivirus
b. Canine parvovirus
c. Feline herpesvirus
d. Feline parvovirus
e. Canine rotavirus

A

A. and C.

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8
Q

Which of the follow viruses have high frequency of mutations

a. Canine parvovirus
b. Canine coronavirus
c. Canine rotavirus
d. Canine

A

B.

It is a RNA virus

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9
Q
  1. What is SN used for?
    a. Measure the virus concentration
    b. Measure infectivity of antibody
    c. Measure the concentration of antibody
    d. Measure TCID50/ml
A

C.

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10
Q

Which virus is easy to inactivate or disinfect?

a. Feline parvovirus
b. Feline herpesvirus
c. Feline rotavirus
d. Canine adenovirus

A

B. because it is enveloped

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11
Q

Can EHV-1 viral DNA be found in the trigeminal ganglion and the T cells from an animals recovered from EHV-1 infections?

A

YES

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12
Q

Where does BHV-1 become latent?
What about betaherpesvirinae like porcine cytomegalovirus?
What about gammaherpesvirinae like malignant catarrhal fever?

A

Trigeminal ganglia
Salivary glands, kidneys, and lymphocytes
Lymphoid cells

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13
Q

What sample should you take from the sick animal if you suspect the animal has BHV-2 infection?

A

Skin scrape and serology

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14
Q

T/F? Feline herpesvirus is different from equine herpesvirus in morphology and genome replication.

A

False

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15
Q

What is different between the three different herpesvirus subfamilies?

a. Morphology
b. Replication
c. Host
d. Biologic activities in diseases and tissue tropism within the infected host

A

C. and D.

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16
Q

What is latent infection?

a. The virion hides inside the nucleus
b. Viral genome hides inside of the cytoplasm
c. Viral capsids hide inside of the neurons
d. Viral genomes hides inside the nucleus

A

D.

17
Q
  1. What are tissues susceptible to alphaherpesvirus infection?
    a. Enterocytes
    b. Mucosal epithelial cell
    c. Corneal epithelial cells
    d. Neurons
    e. Reproductive system
A

All except A.

18
Q
  1. What diseases are associated with alphaherpesvirus infection?
    a. Respiratory
    b. Ocular diseases
    c. CNS diseases
    d. Reproductive diseases
    e. Hemorrhagic disease
A

ALL

19
Q
  1. What is the unique feature of Marek’s disease virus?
A

Polyclonal T Lymphocytes Tumors

20
Q

s herpesviridae enveloped or non-enveloped?

A

Enveloped

21
Q

What is latent infection?

a. Animals with latent infection are sick and showing clinical signs
b. Not sick and do not have clinical symptoms
c. Sick, showing clinical symptoms, and are shedding virus
d. Not sick, not showing clinical symptoms, and are not shedding the virus

A

D.

22
Q

How do the herpesviruses maintain a latent infection?

a. Virions hide in an immune privileged tissue
b. Leave their genome in an immune privileged tissue
c. Leave their genome in the cytoplasm of an immune privileged cell
d. Leave their genome in the nucleus of an immune privileged cell
e. Integrate their genome into the host chromosome
f. Leave their genome as an episome in the nucleus

A

D. and F.

23
Q

What is the difference in eye disease caused by FIP vs. FHV?

A

a. FHV has lots of inflammation and leads to the formation of corneal ulcers
b. FIP has immune complex formation that activates complement (opacity due to enzyme leakage)

24
Q

What is common between feline herpesvirus and equine herpesvirus?

A

Everything except the host

25
Q

What is the common disease associated with alphaherpesvirus infection in the pregnant animals?

A

Abortion

26
Q

What tissues are affected by PrV (porcine herpesvirus) infection?

A

It is the gammaherpesvirinae subfamily that replicates and latent in lymphoid cells. It is lymphoproliferative and can transform cells.

Virology (12 decks)

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