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Micro-EX2- Tye > Herpes & papillomavirus - Middleton > Flashcards

Herpes & papillomavirus - Middleton Flashcards

1
Q

What are the 5 key characteristics of Alphaherpes virus?

A
  • Variable host range
  • Short Reproduction cycle
  • Rapid spread in culture
  • Efficient destruction of infected cells
  • Capacity to establish latency in sensory ganglia
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2
Q

Herpes Type 1 Famliy, genome & Virion…

A 
Family = Alphaherpesviridae
Genome = dsDNA
Virion = enveloped
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3
Q

Herpes type 2 family, genome & virion…

A 
Family = aplhaherpesviridae
Genome = dsDNA
Virion = enveloped
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4
Q

Cytomegalovirus Family, genome & virion

A 
Family = Betaherpesviridae
Genome = dsDNA
Virion = enveloped
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5
Q

Epstein-Barr family, genome & virion

A 
Family = Gammaherpesviridae
Genome = dsDNA
Virion = enveloped
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6
Q

Human papilloma virus family genome & virion..

A 
Family = Papillomaviridae 
Genome = dsDNA
Virion = Non enveloped!
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7
Q

What types of herpes simplex infections exists?

A
  • Ocular
  • Oral
  • Genital
  • Neonatal
  • Meningoencephalitis
  • encephalitis
  • Disseminated herpes
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8
Q

Transmission of Alphaherpes virus 1 (HSV-1)?

A

Oral - Oral
Oral - genital
*2/3 rds of adults are seropositive

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9
Q

Transmission of HSV-2?

A
  • Primarily genital-genital although oral to genital is possible. *Approx 1/5 of adults are infected.
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10
Q

Alphaherpes virus: incubation, symptoms and recovery…

A

incubation = 2-14 days (typically 4-5)
Symptoms = flu-like, localized lesions (Cold sores)
Recovery after 8-12 days

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11
Q

Prevention & Treatment of alphaherpes…

A
  • Avoid kissing & sex during active herpes occurrence.

- Treatment = Acyclovir can be used to limit virus replication.* will not eliminate latent infections.

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12
Q

What are the 7 key characteristics of Betaherpes virus?

A
  • restricted host range
  • Long reproductive cycle
  • slow progression in cell culture
  • Enlargement of infected cells
  • Carrier cultures
  • latent infection in a variety of tissues
  • Prototypical member: cytomegalovirus (CMV)
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13
Q

What are the 5 key characteristics of Gammaherpes virus?

A
  • Restricted host range
  • Targets T & B lymphocytes
  • Lytic infections
  • latency in lymphoid tissues
  • Prototypical member: Epstein-barr virus (EBV)
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14
Q

____ is associated with carcinomas. (tumors in jaw, eye socket, ovaries)

A

Epstein-Barr Virus

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Micro-EX2- Tye (12 decks)

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