Herpes cases

Question 1

Epstein Barr Virus symptoms

Answer 1

high fever, malaise, pharyngitis, adenopathy, fatigue, reaction to amoxicillin, spleen enlargement

Question 2

Transmission of epstein barr virus

Answer 2

person to person via saliva

Question 3

Site of latency of epstein barr

Answer 3

B cells

Question 4

Target cell of epstein barr

Answer 4

epithelial cells and B cells. Attaches via C3D component of complement

Question 5

Epstein barr class

Answer 5

Gamma

Question 6

Epstein barr primary infections..

Answer 6

most are asymptomatic

Question 7

Epstein barr diagnoses

Answer 7

B cells produce IgM antibody (positive heterophile antibody)
atypical lymphocytes

Question 8

Cytomegalovirus (CMV) symptoms

Answer 8

microcephaly, jaundice, hepatospenomegaly, deafness, can eventually lead to mono

Question 9

Transmission of CMV

Answer 9

blood; transplacental spread from primary infection in mom during pregnancy; oral secretions; sexual contact; organ transplant

Question 10

Site of latency of CMV

Answer 10

monocytes

lymphocytes

Question 11

Diagnoses of CMV

Answer 11

CMV in the infants urine

Question 12

Class of CMV

Answer 12

Beta

Question 13

Immunity required to control CMV

Answer 13

cell mediated

Question 14

Treatment for CMV

Answer 14

ganciclovir for AIDS patients; immunoglobin + G

Question 15

HSV 1 and HSV 2 symptoms

Answer 15

small vessicles with erythema, itching

Question 16

Transmission of HSV

Answer 16

HSV1: close contact

HSV 2: sexual contact

Question 17

Target cell of HSV

Answer 17

epithelial cell of mucosa

Question 18

Site of latency of HSV

Answer 18

ganglia of neurons

Question 19

Diagnoses of HSV

Answer 19

isolation of virus from herpetic lesions

Question 20

Treatment of HSV

Answer 20

acyclovir, valacylovir, and famicylovir which inhibit DNA synthesis

Question 21

Class of HSV

Answer 21

alpha

Question 22

Immunity required for control of HSV

Answer 22

cell mediated

Question 23

Varicella Zoster symptoms

Answer 23

painful dermatomal rash, starts at head then progresses to extremities,

Question 24

Transmission of VZV

Answer 24

respiratory droplets, close contact

Question 25

Site of latency of VZV

Answer 25

neural sensory ganglia

Question 26

Diagnoses of VZV

Answer 26

direct fluroescent antibody stainings of scrapings from lesions is rapid, sensitive, and specific

Question 27

Treatment for VZV

Answer 27

DNA polymerase inhibitors like acyclovir, famicyclovir, and valacyclovir

Question 28

Vaccine for VZV?

Answer 28

live virus for children

Question 29

Characteristics of VZV

Answer 29

large, enveloped virus with d.s. DNA genome

Question 30

Tzanck smear

Answer 30

scraping of cells from vesicular lesions testing for the presence of multinucleated giant cells

Question 31

Treating with amoxicillin mistakedly can cause a rash with this disease

Answer 31

epstein barr virus

Question 32

lymphoctyosis

Answer 32

larger than normal number of T lymphocytes

Question 33

Diagnostic indicator of EBV

Answer 33

heterophile antibody