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Medical Microbiology Test 2 > Herpes cases > Flashcards

Herpes cases Flashcards

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Biology 101 flashcards USMLE® Step 1 flashcards
1
Q

Epstein Barr Virus symptoms

A

high fever, malaise, pharyngitis, adenopathy, fatigue, reaction to amoxicillin, spleen enlargement

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2
Q

Transmission of epstein barr virus

A

person to person via saliva

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3
Q

Site of latency of epstein barr

A

B cells

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4
Q

Target cell of epstein barr

A

epithelial cells and B cells. Attaches via C3D component of complement

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5
Q

Epstein barr class

A

Gamma

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6
Q

Epstein barr primary infections..

A

most are asymptomatic

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7
Q

Epstein barr diagnoses

A

B cells produce IgM antibody (positive heterophile antibody)
atypical lymphocytes

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8
Q

Cytomegalovirus (CMV) symptoms

A

microcephaly, jaundice, hepatospenomegaly, deafness, can eventually lead to mono

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9
Q

Transmission of CMV

A

blood; transplacental spread from primary infection in mom during pregnancy; oral secretions; sexual contact; organ transplant

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10
Q

Site of latency of CMV

A

monocytes

lymphocytes

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11
Q

Diagnoses of CMV

A

CMV in the infants urine

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12
Q

Class of CMV

A

Beta

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13
Q

Immunity required to control CMV

A

cell mediated

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14
Q

Treatment for CMV

A

ganciclovir for AIDS patients; immunoglobin + G

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15
Q

HSV 1 and HSV 2 symptoms

A

small vessicles with erythema, itching

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16
Q

Transmission of HSV

A

HSV1: close contact

HSV 2: sexual contact

17
Q

Target cell of HSV

A

epithelial cell of mucosa

18
Q

Site of latency of HSV

A

ganglia of neurons

19
Q

Diagnoses of HSV

A

isolation of virus from herpetic lesions

20
Q

Treatment of HSV

A

acyclovir, valacylovir, and famicylovir which inhibit DNA synthesis

21
Q

Class of HSV

A

alpha

22
Q

Immunity required for control of HSV

A

cell mediated

23
Q

Varicella Zoster symptoms

A

painful dermatomal rash, starts at head then progresses to extremities,

24
Q

Transmission of VZV

A

respiratory droplets, close contact

25
Q

Site of latency of VZV

A

neural sensory ganglia

26
Q

Diagnoses of VZV

A

direct fluroescent antibody stainings of scrapings from lesions is rapid, sensitive, and specific

27
Q

Treatment for VZV

A

DNA polymerase inhibitors like acyclovir, famicyclovir, and valacyclovir

28
Q

Vaccine for VZV?

A

live virus for children

29
Q

Characteristics of VZV

A

large, enveloped virus with d.s. DNA genome

30
Q

Tzanck smear

A

scraping of cells from vesicular lesions testing for the presence of multinucleated giant cells

31
Q

Treating with amoxicillin mistakedly can cause a rash with this disease

A

epstein barr virus

32
Q

lymphoctyosis

A

larger than normal number of T lymphocytes

33
Q

Diagnostic indicator of EBV

A

heterophile antibody

Medical Microbiology Test 2 (8 decks)

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