Heredity/Mendelian Genetics Flashcards

1
Q

How is metaphase I of meiosis different from metaphase of Mitosis?

A

In metaphase I of meiosis, chromosome pairs line up together. In mitosis, single chromosomes line up one by one.

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2
Q

What are the stages of meiosis and how do they compare to Mitosis?

A

Meiosis has two rounds of cell division (Meiosis I and II), each with prophase, metaphase, anaphase, and telophase, creating four unique haploid cells, while mitosis has one round with the same stages but produces two identical diploid cells.

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3
Q

What are homologous chromosomes and how many do humans and fruit flies have?

A

Homologous chromosomes are a pair of chromosomes, one from each parent, that have the same genes. humans have 23 pairs; fruit flies have 4 pairs.

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4
Q

What is crossing over and when does it occur?

A

Crossing over swaps DNA between homologous chromosomes in prophase I; increases genetic diversity.

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5
Q

How many male gametes are formed from one spermatocyte?

A

Four sperm from one spermatocyte.

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6
Q

How many female gametes are formed from one oocyte and how many polar bodies are created?

A

One egg and three polar bodies from one oocyte.

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7
Q

What is the only immortal cell humans have?

A

Egg cells are the only immortal human cells.

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8
Q

How do we differentiate males from females in plants and animals based on cell type and motility?

A

Males make small, motile gametes; females make large, non-motile ones.

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9
Q

How many autosomes do humans have and what are the sex chromosomes?

A

Humans have 44 autosomes; sex chromosomes are X and Y.

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10
Q

What are bird sex chromosomes?

A

Birds use Z and W.

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11
Q

What is a Karyotype?

A

A karyotype is a picture of all the chromosomes in a cell, arranged by size and shape. It helps check for chromosome problems.

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12
Q

What are the steps to create a karyotype for a human?

A

Collect cells, stop division, stain, photograph, arrange.

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13
Q

What type of disorders are karyotypes used to diagnose?

A

Karyotypes diagnose chromosomal disorders like Down syndrome.

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14
Q

How many chromosomes do all non-human primates have?

A

Non-human primates have 48 chromosomes.

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15
Q

Why do humans have 2 fewer chromosomes than non-human primates?

A

Humans have 46 due to fusion of two ancestral chromosomes.

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16
Q

What does a female calico cat tell us about the X chromosomes in a female?

A

Calico cats show X-inactivation; each cell expresses one X randomly.

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17
Q

What is the key gene on the Y chromosome that is not found on the X chromosome?

A

SRY gene determines male sex and is only on Y chromosome.

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18
Q

How does chromosome number determine sex in bees?

A

In bees, females develop from fertilized eggs and are diploid; males develop from unfertilized eggs and are haploid.

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19
Q

What determines sex in turtles?

A

Turtle sex depends on temperature during egg incubation.

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20
Q

Who is the father of genetics?

A

Gregor Mendel is the father of genetics.

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21
Q

What organism did Gregor Mendel study?

A

He studied pea plants.

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22
Q

What are the male parts of a flower?

A

Male flower parts: anther and filament (stamen).

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23
Q

What are the female parts of a flower?

A

Female flower parts: stigma, style, ovary (carpel).

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24
Q

What enlarges into a fruit?

A

Ovary enlarges into fruit.

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25
What do we call a fertilized egg that develops inside the fruit?
Fertilized egg is a zygote.
26
What are the three types of plants that came before flowering plants?
Mosses, ferns, and gymnosperms.
27
What is Mendel's first law?
Mendel's first law, the Law of Segregation, says each parent gives just one of their two genes to their child.
28
What experiment did Mendel do that no one else thought to do?
He tracked traits through F1 and F2 generations to reveal patterns.
29
What is the famous phenotype ratio observed in the offspring when two heterozygous individuals are crossed for one trait?
3:1 phenotype ratio for monohybrid heterozygous cross.
30
What is Mendel's second law?
Mendel’s second law, the law of Independent assortment, says traits are passed down independently.
31
What is the famous phenotype ratio observed in the offspring when crossing two heterozygous individuals for two traits?
9:3:3:1 phenotype ratio in dihybrid heterozygous cross.
32
How many different ways can 23 pairs of chromosomes assort?
2²³ = over 8 million combinations from independent assortment.
33
What is nondisjunction?
Nondisjunction is failed chromosome separation.
34
What condition does nondisjunction of chromosome 21 cause?
Causes Down syndrome with chromosome 21.
35
What is an allele?
An allele is a version of a gene.
36
How many alleles do you have for one gene?
You have two alleles for each gene, one from each parent.
37
Distinguish between dominant and recessive genes.
Dominant genes show their trait even if there's only one copy; recessive genes need two copies to show.
38
Distinguish between homozygous and heterozygous.
Homozygous means two of the same alleles, heterozygous means two different ones.
39
Distinguish between 1N/2N, Diploid/Haploid/Polyploid.
1N means one set of chromosomes (haploid), 2N means two sets (diploid). Polyploid means more than two sets.
40
What types of Punnett squares should you be able to do?
Monohybrid, dihybrid, sex-linked, blood type, codominant, incomplete dominance.
41
Why are males at a disadvantage for genes on the X-chromosome?
Males have only one X chromosome, so one bad gene shows up immediately.
42
What sex-linked condition was spread through the Houses of Europe originating with Queen Victoria?
Hemophilia was passed through royal families from Queen Victoria.
43
What would we call Queen Victoria since she had the gene for hemophilia but no symptoms?
She was a carrier.
44
Know the three alleles in the population for blood type.
The three blood type alleles are A, B, and O.
45
How many possible gametes can a dihybrid cross produce?
A dihybrid cross can make 4 different gametes.
46
How many possible gametes can a trihybrid cross produce?
A trihybrid cross can make 8 different gametes.
47
Distinguish codominance from incomplete dominance in terms of phenotypes.
In codominance, both traits show up fully; in incomplete dominance, the traits blend together.
48
By what type of selection has teosinte changed into modern corn?
Teosinte became modern corn through artificial selection.
49
What is pleiotropy?
Pleiotropy occurs when one gene affects multiple traits.
50
Give one example of pleiotropy.
The gene responsible for sickle cell anemia affects red blood cells, oxygen transport, and can also cause pain and organ damage.
51
What is polygenic inheritance?
Polygenic inheritance means many genes work together to affect one trait.
52
Give one example of polygenic inheritance.
Height is a common example.
53
How many genes code for skin color?
Skin color is controlled by about 169 genes.
54
How many genes affect eye color?
Eye color is affected by 16 genes.
55
What does epistasis mean?
Epistasis is when one gene can hide or change the effect of another.
56
Give an example of epistasis.
In labs, one gene decides color, another decides if color shows.
57
What is the nature vs nurture concept?
Environment can change how genes work.
58
Give an example how the environment can override genetics in an organism's phenotype.
In Labrador retrievers, one gene controls coat color, but another gene can block the color entirely.
59
What is a pedigree?
A pedigree is a chart showing family traits.
60
How are males and females distinguished in a pedigree?
Circles are females, squares are males, and lines connect parents to children.