Hepatopatia Alcohólica Flashcards

1
Q

3 lesiones principales

A

Hígado graso
Hepatitis alcohólica
Cirrosis

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2
Q

Cuantos alcohólicos desarrollan hepatitis alcohólica

A

10-20%

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3
Q

Calculo de alcohol y apartir de cuanto inicia riesgo

A

1 cerveza, 120ml vino, 30ml destilados contienen 12g de alcohol

20-50mg día riesgo de cirrosis; 160g/dia por 10-20 años hepatitis o cirrosis

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4
Q

Características histologicas de la hepatitis

A

Lesión del hepatocito, necrosis irregular, polimorfonucleares y fibrosis, cuerpos de Mallory-Denk

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5
Q

Manifestaciones de laboratorio

A

Elevacion de GGTP, AST Y ALT (cociente de 1) menor a 400 UI, hipertrigliceridemia e hiperrubilinemia.

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6
Q

Calculo de la función discriminadora para identificar mal pronóstico

A

4.6 X (Prolongación de PT) + bilirrubina

>32 se considera hepatitis grave

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7
Q

Clasificación de MELD

A

Bilorrubina + INR + Creatinina
6-40
Para prioridad en la lista de transplante
Predictor de mortalidad a 3 meses

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8
Q

Tratamiento para hepatitis alcohólica grave

Indice de discriminación >32 y MELD > 20

A

40 mg/dia prednisona

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