Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Radiology > Hepatopancreatobiliary System > Flashcards

Hepatopancreatobiliary System Flashcards

1
Q

Prognosis of fibrolamellar HCC vs HCC?

A

Often resectable and better Px (60% 5 year survival)

HCC: 30% 5 year survival

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Most common cause of HCC?

A

Developing countries: Hep B, Hep C and aflatoxin

Western world: alcohol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Acute fatty liver of pregnancy?

A

Spectrum from mild hepatic dysfunction to failure, coma, death

Congenital deficiency causing defect in mitochondrial fatty acid oxidation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

7 cm green tumour in liver with cirrhosis and UC?

A

HCC

Note cholangiocarcinoma is fibrous and has firm/ gritty consistency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which cell causes excess collagen production in cirrhosis?

A

Hepatic stellate or Ito cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Least likely to cause irregular bile ducts on ERCP?

A

SLE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Caroli disease and hepatic fibrosis?

A

Involves large IHBD without fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fibrosis in PSC vs PBC?

A

PSC: periductal onion-skin fibrosis

PBC: portal fibrosis, nodular regeneration and cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most common cause of liver disease in pregnancy?

A

Cholestasis

Viral infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cholangiocarcinoma- differentiation and nodal mets?

A

Typically well to moderately differentiated

50-75 % have mets to regional nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Stains for Cu and Fe on liver histology?

A

Cu: Rhodamine stain

Fe: Prussian blue (blue-black colour)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Green tumour in non-cirrhotic liver?

A

Adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DNA virus in liver?

A

Hep B (all others RNA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Does acute pancreatitis cause hypocalcaemia?

A

YES

Precipitation of calcium salts in necrotic fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cholesterol vs pigment stones?

A

85% cholesterol (only 15% radio-opaque)

15% pigment (from unconjugated bilirubin- black 60% radio opaque and brown radiolucent)

Both have glycoprotein matrix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Jaundice in neonate: physiological vs biliary atresia?

A

Physiological should NOT be seen beyond 2 weeks

Otherwise, consider biliary atresia: intra and extra-hepatic fibrosis which progresses to cirrhosis within 3-6 mths if untreated

17
Q

What percentage of people with gallstones develop pancreatitis?

A

Only 5%

Note viruses (coxsakie, mumps, HSV etc) can cause acute pancreatitis

18
Q

Least likely location for ectopic pancreas?

A

Colon

19
Q

Autoimmune pancreatitis- LN? Name 3 features.

A

LN is RARE

Focal or diffuse (more common) pancreatic swelling

Irregular narrowing of MPD

Biliary tree involvement

20
Q

Name 5 genetic mutations associated with pancreatitis and adenocarcinoma

A

Peutz-Jegher, BRCA2, SPINK

CDKN2A

PRSS-1

21
Q

Peliosis hepatis- signal on MRI?

A

Multiple blood filled cysts within liver.

Low T1, high T2 , centrifugal enhancement

HIV, TB, HCC, chemoRx

22
Q

Chronic hepatitis- which virus implicated?

A

10% Hep B

80% Hep C

23
Q

Histology of autoimmune hepatitis?

A

Clusters of plasma cells in the interface of portal tracts and hepatic lobules

24
Q

Haemochromatosis more common in males or females?

A

6X more common in males

Women protected by menstruation

25
Q

Haemochromatosis and adrenals?

A

Can cause Addison’s disease due to haemosiderin deposition

26
Q

FNH- contents and location?

A

Contains normal hepatocytes, kuppfer cells and bile ducts

No normal PV

Subcapsular location, well demarcated but not encapsulated

27
Q

Thrombocytopaenia from platelet sequestration within liver haemangioma?

A

Kasabach Merritt syndrome

28
Q

Focal GB wall thickening- 2 DDx

A

Adenomyomatosis

Cholesterolosis: strawberry GB and multiple polyps

29
Q

4 stages of pancreatic adenocarcinoma

A

Stage 1: less than 2 cm

Stage 2: more than 2 cm

Stage 3: beyond pancreas but not coeliac axis/ SMA

Stage 4: involves coeliac axis/ SMA (unresectable)

Note: nodal involvement means stage 2 or greater

30
Q

Most likely to benefit from phototherapy?

A

Criggler-Najjar (AR disorder of bilirubin metabolism)

Radiology (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions