hepatocellular carcinoma? Flashcards
1
Q
define hepatocellular carcinoma?
A
● Primary malignancy of the liver parenchyma
2
Q
what is the main risk factor for hepatocellular carcinoma?
A
cirrhosis
3
Q
what are the most common causes of hepatocellular carcinoma?
A
● Hepatitis B- most common cause world wide
● Hepatitis C – most common cause in Europe
4
Q
what is the epidemiology of hepatocellular carcinoma?
A
● Third most common cause of cancer worldwide
● LESS common than liver metastases
5
Q
what are the presenting symptoms of hepatocellular carcinoma?
A
o Abdominal distension o jaundice o ascites o RUQ pain o Hepatomegaly o Pruritis o Splenomegaly o Constitutional symptoms o History of Exposure to Carcinogens
6
Q
first line investigations for hepatocellular carcinoma?
A
o AFP and abdominal USS
7
Q
what is the gold standard investigation for staging?
A
o CT/MRI
