Hepatitis Flashcards

1
Q

What is hepatitis?

A

Inflammation of the liver and destruction of hepatocytes

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2
Q

What viruses cause hepatitis?

A

Hepatotropic viruses- they have an effect on the liver

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3
Q

What are the symptoms of hepatitis

A

Jaundice- yellowing of eyes/skin, elevated levels of transaminases present in the blood

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4
Q

What hepatotropic viruses are there?

A

Hepatitis A-E

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5
Q

Hepatitis C transmission?

A

Bloodborne

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6
Q

Hepatitis B transmission?

A

Bloodborne, unprotected sex, mother to baby

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7
Q

Hepatitis D can only infect those infected with?

A

Hepatitis B

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8
Q

Which hepatotropic viruses can cause chronic infection?

A

Hepatitis B, C and D

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9
Q

Genome of hepatitis C?

A

+ssRNA

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10
Q

Genome of hepatitis B?

A

dsDNA-RT

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11
Q

Baltimore classification of hepatitis C?

A

Group IV

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12
Q

Baltimore classification of hepatitis B?

A

Group VII

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13
Q

Is there a vaccine for hepatitis C?

A

No

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14
Q

Is there a vaccine for hepatitis B?

A

Yes

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15
Q

Is hepatitis B curable?

A

No

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16
Q

Is hepatitis C curable?

A

Yes

17
Q

Hepatitis A and E are spread via?

A

Fecal oral route

18
Q

Which people are most likely to develop chronic HBV infection?

A

Children

The risk decreases with age

19
Q

When was HBV added to the routine vaccination programme in the UK?

A

2017

20
Q

HCV symptoms in the beginning?

A

There are no symptoms of early infection

Tends to be asymptomatic

21
Q

Hepatitis D can only infect individuals already infected with?

A

Hepatitis B

22
Q

Chronic infection can progress to?

A

Liver cirrhosis, carcinomas or liver-failure

23
Q

HBV is more infectious than HIV by how many times?

A

100 times more infectious than HIV

24
Q

Children infected with HBV are at the greatest risk of developing?

A

Chronic infection

25
Q

HBV genome?

A

dsDNA-RT

26
Q

HCV genome?

A

+ssRNA

27
Q

Majority of HCV infections become?

A

Chronic

28
Q

Majority of individuals infected with HCV develop?

A

Chronic infection

29
Q

What determines susceptibility to developing chronic HBV infection?

A

The age you are infected at

The young are much more vulnerable

30
Q

Which hepatoviruses are spread through the fecal-oral route?

A

HEV and HAV

31
Q

Which hepatoviruses result only in acute infection?

A

HEV and HAV