Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MM- Viruses > HCV/HBV treatment > Flashcards

HCV/HBV treatment Flashcards

1
Q

Which virus was discovered first?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which virus is curable?

A

HCV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which virus is incurable?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Why is HBV incurable?

A

Due to the maintained cccDNA pool in the nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which virus is there a vaccine for?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Routine vaccination of HBV began when in the UK?

A

2017

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which virus replicates in the cytoplasm?

A

Both HBV and HCV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which virus has a dsDNA genome?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which virus has +ssDNA genome?

A

HCV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

You are more likely to develop chronic HBV infection when?

A

You are younger

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most people infected with HCV develop?

A

Chronic infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which virus has a higher viraemia?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which virus is more genetically diverse?

A

HCV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which virus enters the nucleus?

A

HBV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Can HBV be cured?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

HCV can be cured by use of?

A

Antivirals

17
Q

Antiviral targets?

A

NS5B polymerase
NS5A which forms the membranous web
NS3/4A protease

18
Q

Which drug can target replication?

A

Ribavirin

19
Q

What is ribavirin?

A

Chain terminator

Nucleoside analogue

20
Q

Which drug can inhibit the NS5B polymerase?

A

Sofosbuvir

21
Q

Which drug can inhibit NS3/4A protease?

A

Telaprivir

22
Q

What else can treat hepatitis infection?

A

PEGylated interferon

23
Q

What is the function of PEG?

A

Makes the interferon last longer in the blood- fewer administrations required

24
Q

HBV vaccine is made up of?

A

HBsAg subviral particles

25
Q

How is the HBV vaccine made?

A

GM subunit

26
Q

GM what is made?

A

GM yeast containing the gene for HBsAg and expressing HBsAg

27
Q

What yeast?

A

Saccharomyces cereviseae

28
Q

2018 who tested HBV on liver-on-a-chip?

A

Marcus Dorner at Imperial College

MM- Viruses (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions