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Viruses & Parasites > Hepatitis > Flashcards

Hepatitis Flashcards

1
Q

How is Hep A transmitted?

A

Fecal-oral

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2
Q

How is Hep B transmitted?

A

Blood - IVDU and needles
Sexual
Mom –> fetus

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3
Q

How is Hep C transmitted?

A

Blood - IVDU and needles

Sex - more unlikely

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4
Q

How is Hep D transmitted?

A

Blood

Same as B since present together

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5
Q

How is E transmitted?

A

Fecal-oral

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6
Q

What does high transaminases (ALT/AST) indicate?

A

Hepato-cellular injury, necrosis, death

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7
Q

What is the likely outcome of Hep A infection in adults?

A

Fully recovery

No chronic damage or cancer

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8
Q

What is the likely disease process and outcome of Hep A infection in kids?

A

Less severe disease - likely asymptomatic

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9
Q

What is the disease outcome of Hep B infection in adults?

A

Highest chance for full recovery
Chance of:
- Chronic hepatitis
- Higher risk of fulminant (sudden onsent) hepatitis

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10
Q

What complication is associated with Hep B in kids?

A

Higher risk of chronic hepatitis

But again, disease is likely to be less severe in kids

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11
Q

What is the Hep A vaccine?

A

Killed virus

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12
Q

What is the Hep B vaccine?

A

Recombinant surface antigen

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13
Q

Which has the highest risk of transmission via needle stick: HIV, Hep B, or Hep C?

A

Hep B!!

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14
Q

What do you give for Hep B prophylaxis?

A

Hyper immune gloublin + vaccine

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15
Q

Hep C prophylaxis

A

IFNa if acute infection develops

Otherwise monitor

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16
Q

Causes of cirrhosis

A

Alcohol
Hep B & C
Congenital
Toxins/meds

17
Q

Treat Hep B

A

RT inhibitors: tenofovir

Pegylated IFNa

18
Q

Treat Hep C

A

IFNa + ribavirin + protease inhibitor (telaprevir or boceprevir)

19
Q

What stage of infection is Hep C Ab neg but RNA present?

A

Acute

20
Q

What stage of infection is Hep Ab neg and RNA neg?

A

Not infected!!

21
Q

What stage of infection is Hep C Ab + RNA +?

A

Active chronic?

22
Q

What stage of infection is Hep C Ab+ RNA -?

A

Previous/resolved/not ongoing Hep C infection

23
Q

Which Hep C genotype is most common throughout the US?

A

Type 1a

Viruses & Parasites (21 decks)

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