Hepatic/Biliary Flashcards
lab test used to monitor hepatitis, cirrhosis, or treatments that can be harmful to the liver
ALT
lab value that shows damage to any tissue with high metabolic activity such as the heart, liver, or kidneys
AST
lab values that indicate biliary cholestasis (gallstones) or alcohol abuse
GGT and GGTP
4 things albumin is low in
cirrhosis
ascites
chronic hepatitis
poor nutrition
lab test that is similar to albumin but shows up faster for acute malnutrition
pre-albumin
lab value that is elevated in liver disease and does not respond to vitamin K in the presence of severe liver damage
prothrombin time
ammonia levels _____ in liver disease and cause changes in mental status
increase
3 lab values that will be increased in a biliary obstruction
HDL
LDL
cholesterol
most common complication of liver biopsy
peritonitis
jaundice occurs when bilirubin levels are greater than ___ mg/dL
2
_______ jaundice is caused by the inability of damaged liver cells to clear normal amounts of bilirubin from the blood
hepatocellular
_______ jaundice is caused obstruction of the bile duct, an inflammatory process, or an enlarged organ
obstructive
_______ jaundice is caused by increased destruction of RBC more than the deliver can handle
hemolytic
ascites is affected by the movement of _______ from the serum into the peritoneal cavity
albumin
removal of fluid from the abdomen from a small hole puncture
paracentesis
surgery to treat ascites that inserts a stent to act as a shunt between the portal circulation and the hepatic vein
TIPS
vitamin ____ deficiency leads to eye and skin changes, night blindness
A
______ deficiency leads to Wernickes-Korasakoff psychosis, beriberi, and polyneuritis
thiamine
______ deficiency leads to lesions in the skin and mucous membranes
riboflavin
_______ deficiency leads to lesion in the skin and mucous membranes and neurologic changes
pyridoxine
vitamin ____ deficiency leads to scurvy (hemorrhagic disease)
C
vitamin ___ deficiency can leads to bleeding and low platelets
K
_____ ____ deficiency can lead to macrocytic anemia
folic acid
_____ liver tumors typically occur in women taking oral contraceptives
benign
4 things that cause primary liver tumors
chronic liver disease
hep C
hep B
cirrhosis
_____ ____ is elevated in primary liver cancer
alpha fetoprotein
______ _____ is elevated in cancers of the GI tract
carcinoembryonic agent (CEA)
the ____ score is used to determine allocation of the liver
MELD
the ______ functions as a storage depot for bile
gallbladder
pancreatic enzyme that digests carbs
amylase
pancreatic enzyme that digests protein
trypsin
pancreatic enzyme that digests fat
lipase
patient must be ____ before ultrasonography
NPO
____ scan is when IV dye is given to track flow through biliary tract
HIDA
older people are more likely to develope _______
gallstones
older people have atypical ______ disease presentation
gallbladder
obstructive jaundice causes dark _____ to _____ urine and _____ colored stools
orange to brown, clay
obstructed blood floe through the liver results in ______ _____
portal hypertension
2 things portal hypertension can lead to
ascites
esophageal varices
1st choice diuretic for ascites
aldosterone
2nd choice diuretic for ascites
lasix
diuretic NOT to give with ascites because it can cause hepatic encephalopathy
Diamox
procedure for ascites where they insert a needle and draw out the fluid
paracentesis
treatment for ascites that pulls blood from abdomen back into vascular system
peritoneovenous shunt
2 things to avoid with ascites
NSAIDs and alcohol
esophageal varices develop when blood flow to the _____ is blocked
liver
esophageal varices are the most significant source of bleeding in ______
cirrhosis
emergency vasoconstrictor given to treat esophageal varices
vasopressin
3 medications for esophageal varices
octreotide (sandostatin)
beta-blockers
nitrates
give vitamin ___ to treat esophageal varices
K
3 things to avoid with esophageal varices
alcohol
NSAIDs
salicylates
hepatic encephalopathy is caused by increased _____
ammonia
3 symptoms othered than AMS for hepatic encephalopathy
asterixis
constructional apraxia
fector hepaticus
inability to sustain posture and involuntary movements
asterixis
inability to draw out what someone tells you or shows you
constructional apraxia
sweet smelling poop seen in complete liver failure
fector hepaticus
medication that causes excretion of ammonia in poop
Lactulose (cephulac)
3 medications used for hepatic hydrocepaholpathy
lactulose (cephulac)
IV glucose
antibiotics
Hep A transmission route
fecal-oral route or sex
vaccine is available for both Hep ___ and ___
A and B
Hep A recovery
mild to full
Hep B transmission route
blood and fluids
Hep B can be acute or chronic, but is mostly _____
chronic
Hep B symptoms usually don’t appear until __ to ___ months after infection
1 to 4
3 things Hep B increases risk for
chronic hepatitis
cirrhosis
cancer
Hep C transmission route
blood and sex
there is a potential cure for Hep __
C
Hep __ occurs in some cases of Hep B
D
patients with Hep D are more likely to develop ______ _____ ______
fulminant liver failure
to be diagnosed with Hep D patients have to have interferon A for ____ ____
one year
Hep E transmission route
fecal-oral
Nonviral hepatitis is _____ induced
drug
number 1 cause of nonviral hepatitis
tylenol
with nonviral hepatitis avoid ___ ____ ____ because it causes you to bleed more
st. johns wart
3 types of toxic hepatitis
alcohol
medicinal
chemical
toxic hepatitis can lead to _____ ______ ___
fulminant liver failure
sudden and severely impaired liver function
fulminate liver failure
medication that can cause liver failure
tylenol
chemical that can cause liver failure
carbon tetrachloride
metabolic disturbance that can cause liver failure
Wisons disease
structural change that can cause liver failure
Budd-Chiari syndrome
antidote for tylenol
N-acetylcysteine
antidote for mushrooms
PCN
treatment where stuff is filtered out fo the blood in liver failure
plasmapahresis
alcoholic cirrhosis is scarring around the ____ ____
portal area
biliary cirrhosis is scarring around the ____ _____
bile ducts
patients with cirrhosis should have _____ calorie diets with low ____
high, sodium
_______ cholecystitis occurs because there is a stone obstructing bile flow
calculous
_______ cholecystitis occurs because of inflammation after trauma or surgery
acalculous
3 antibiotics given with cholecystitis
penicillins
cephalosporins
metronidazole
patients with cholecystitis should have a diet high in _____ and low in _____
protein, fat
the gallbladder is the storage place for _____
bile
the gallbladder metabolizes _____
fat
pill taken that can replaces exocrine pancreas functions
pancrease
inflammation of the gallbladder
cholecystitis
gallbladder stones
cholelithiasis
slowing or stalling of bile through gallbladder
cholestasis
type of gallbladder stones that are more common
cholesterol gallstones
5 F’s risk factors for cholelithiasis
fair
fat
female
fertile
familial
vitamins that will be low in cholelithiasis
A, D, K, E
if you think your patient has gallbladder problems do not give _____ because it causes constriction and more pain
morphine
medications that dissolve gallstones
ursodeoxycholic acid
chenodiol
procedure that breaks up stones
lithotripsy
most common cause of acute pancreatitis is _____ of the pancreas
autodigestion
acute pancreatitis pain is unrelieved by _____
antacids
acute pancreatitis can cause decreased _______
perstalsis
acute pancreatitis will cause ecchymosis around the _____ and _____
flank and umbilicus
someone who has acute pancreatitis will show signs of _____
shock
in acute pancreatitis, _____ and ____ will be 3x the normal limit
amylase, lipase
amylase and lipase will be elevated within the first ____ hours of symptoms and then decrease after ___ to ___ hours
24, 48-72
electrolyte that will be low in acute pancreatitis
calcium
with paracentesis, in acute pancreatitis it may show presence of _____ _____
pancreatic enzymes
someone with acute pancreatitis should have ______ feeding as soon as possible
enteral
acute pancreatitis will cause hyperglycemia, so you must give _____
insulin
2 things acute pancreatitis patients cannot have
alcohol and caffeine
2 most common causes of chronic pancreatitis
smoking and alcohol use
gastric bypass that bypasses the pancreas and is used in patients with chronic pancreatitis
Roux-en-Y