Heparin Flashcards
1
Q
what is heparin
A
An anticoagulant agent
2
Q
what is heparin commonly used with?
A
anticoagulant with antithrombotic properties
3
Q
what happens when you use a small amount of heparin in combination with antithromin III and a heparin cofactor
A
can inhibit thrombosis by inactivating Factor Xa and thrombin (Factor IIa).
4
Q
what happens once active thrombosis has developed?
A
, larger amounts of heparin can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin
5
Q
what does heparin also prevent
A
the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor
6
Q
what is an example of a coagulation test that heparin prolongs?
A
activated partial prothrombin time (aPTT)
