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DIG Biweekly 2 > Henderson- Liver Transplant and Hepatitis > Flashcards

Henderson- Liver Transplant and Hepatitis Flashcards

1
Q

indications name for liver transplants

A

MELD 3.0

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2
Q

liver tranplant evaluation indications:

A

MELD 3.0:
low serum albumin
sex

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3
Q

special indications for liver tranplant

A

HCC
portopulmonary HTN
hepatopulmonary syndrome

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4
Q

____ was made to hopefully increase allocation for liver transplants to sick patients

A

MELD 3.0

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5
Q

special indication for transplant that deals with cirrhotic liver with tumor present

A

HCC

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6
Q

current criteria for liver transplant for HCC patient

A

UCSF

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7
Q

single lesion </= 6.5 cm
</= 3 nodules w/ large </= 4.5cm
maximal tumor burden </=8 cm
no vascular invasion or extrahepatic invasion

A

UCSF criteria

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8
Q

complication of portal HTN and patient has liver cirrhosis and pulmonary HTN

A

Porto-pulmonary HTN

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9
Q

pulmonary vasodilation (takes O2 longer to travel across membrane)

A

porto-pulmonary HTN

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10
Q

dyspnea (sob)
R ventricle overload

A

porto-pulmonary HTN

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11
Q

screening for porto-pulmonary HTN

A

echo

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12
Q

ECHO and pulse ox
main symptom is dyspnea

A

porto-pulmonary HTN

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13
Q

screening tool for hepatopulmonary syndrome

A

Pulse ox (and then ABG if <94%)

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14
Q

to diagnose hepatopulmonary syndrome

A

Echo (seeing bubbles from R to L in heart after third cardiac cycle)

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15
Q

low MELD
transplantation needed due to gastric compression
liver labs normal

A

polycystic liver disease

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16
Q

autoimmune
recurrent cholangitis

A

PSC

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17
Q

risk for rare cholangiocarcinoma
indication for liver transplant

A

PSC

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18
Q

workup for liver transplant for everyone

A

cross sectional abd imaging
ECHO w/ bubbles
pulse ox; ABG

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19
Q

what age to screen for colon cancer

A

45

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20
Q

what age to screen for prostate cancer (PSA)

A

> 50

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21
Q

ischemic heart disease evaluation for low risk patients

A

stress test

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22
Q

ischemic heart disease for evaluation for high risk patients

A

heart cath

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23
Q

what does a liver transplant recipient have to have

A

someone to help them

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24
Q

RNA virus
acute

A

Hep A and E

25
Q

DNA virus
acute
not curable

A

Hep B

26
Q

RNA virus
acute and chronic
treat everyone

A

Hep C

27
Q

incidence of _____ has gone up since COVID

A

Hep A

28
Q

fecal-oral transmission (food handlers, sexual contact, drug abuse)

A

Hep A and Hep E

29
Q

presentation for hepatitis

A

jaundice
RUQ pain
AST/ALT > 1000
hx

30
Q

super infectious and will be really bad for pregnant or immune compromised patients

A

Hep A

31
Q

RNA
acute
patient works on farm (Asia, midwest)

A

Hep E

32
Q

travel hx important for ___

A

Hep E

33
Q

___ and ____ severe in pregnant and immunocompromised patients

A

Hep A and Hep E

34
Q

incorporates host DNA and becomes a part of you (not curable)

A

Hep B

35
Q

DNA virus
acute presentation
10% will develop chronic infection

A

Hep B

36
Q

40 fold more infectious than HIV
PWID (people who inject drugs)
blood transfusion screening

A

Hep B

37
Q

4 diseases where you will see AST/ALT> 1000

A

viral hepatitis
autoimmune hepatitis
Tylenol toxicity
shock liver

38
Q

dx Hep B

A

HBsAg +>6 months

39
Q

can you treat Hep B

A

no, just suppress it

40
Q

treat EVERY patient with this

A

Hep C

41
Q

estimate what with Hep C patient

A

fibrosis

42
Q

Screen_____ for Hep C

A

everyone

43
Q

lives in cytoplasm

A

HCV

44
Q

lives in nucleus

A

HBV

45
Q

normal vaginal intercourse is not a risk for this

A

Hep C

46
Q

extremely sexually transmissible

A

Hep A, E, B

47
Q

if patient w/ HCV has fibrosis (cirrhosis), what are they at risk for

A

HCC

48
Q

fibrosis assessment for HCV if you treat patient

A

Fibroscan

49
Q

antivirals SOFOSBUVIR + LEDIPASVIR

A

to treat Hep C in 8-12 weeks
stop viral genome replication

49
Q

HCV Ab + shows what

A

person has been exposed to Hep C

50
Q

what shows if patient is infected with Hep C

A

viral load (SVR)

51
Q

when to test SVR (viral load) after ending treatment for Hep C

A

12 weeks later

52
Q

SAg+
eAg+
eAb-
AST elevated
DNA (viral load) 20,000

A

treat for Hep B

53
Q

SAg +
eAg-
eAb+
DNA (viral load) 2,000
AST elevated

A

treat for Hep B

54
Q

SAg +
eAg+
eAb-
HBV DNA >100
AST normal

A

dont treat for Heb B

55
Q

SAg+
eAg-
eAb+
HBV DNA >100
AST normal

A

dont treat for Hep B

56
Q

viral load of 200,000 in pregnant woman

A

treat for Hep B

57
Q

this antibody appears after person has cleared Hep B infection

A

HBsAb

DIG Biweekly 2 (11 decks)

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