Hemostasis Flashcards
Vascular Phase
injury to blood vessels causes it to constrict, slowing blood flow.
Platelets
injury to the endothelial lining causes platelets to adhere.
forms a temporary platelet called aggregation. Blood test time(BTT) is used to evaulate the primary stages of hemostasis. also done before surgery.
Coagulation phase
involves a cascade of interactions between coagulation factors that convert from a temporary platelet plug to a fibrin clot.
(Cp) Prothrombin time test(PT/INR)
is used to evaluate the extrinsic pathway. The test also monitors anticoagulant therapy, such as for patients on blood thinners: Documadin. Warfarin, and Heparin.
(CP) INR: International normalized ratio
no matter where you get your blood tested, the ratios will always be calculated correctly to administer medications.
(CP) Partial thromboplastin time(PTT)
is used to evaluate intrinsic pathways.
Note: Any coagulation test such as PTT/PT, must always be drawn from a vein never IV or capillary puncture.
PT/PTT, drawn from light blue top tube and fill completely.
Fibrinolysis
The Breakdown and removal of the clot.
Fibrinolysis Notes
As tissue repair begins, plasmin (an enzyme) breaks down the fibrin clot.
Fibirn Degradation product’s (FDPs) measurements monitors the rate of fibrinolysis.
Hemostasis
Blood Vessels repair after injury