Hemolysis

Question 1

4 places RBC are destroyed during extravascular hemolysis

Answer 1

1. Spleen
2. Lymph nodes
3. Liver
4. Bone marrow

Question 2

How would your patient/ patient’s serum appear if they have extravascular hemolysis

Answer 2

Icteric

Question 3

IMHA

Answer 3

Immune Mediated Hemolytic Anemia

Question 4

What are three causes of hemolysis

Answer 4

1. IMHA
2. Hereditary RBC defects (certain breeds)
3. Toxins

Question 5

What are Heinz bodies

Answer 5

Denatured hemoglobin

Question 6

When toxins cause hemolysis, what will you see in RBC on blood smear

Answer 6

Heinz bodies

Question 7

What 4 substances are considered toxins to animals causing hemolysis evidenced by Heinz bodies

Answer 7

1. Onions
2. Garlic
3. Zinc
4. Acetaminophen

Question 8

IMHA can be primary or secondary. What is primary IMHA

Answer 8

A sudden development of antibodies against own RBC (trigger is unknown)

Question 9

IMHA can be primary or secondary. What is secondary IMHA

Answer 9

An immune response to foreign antigen that results in the animals own RBC destruction

Question 10

4 Causes for secondary IMHA

Answer 10

Neoplasia
Infections
Toxins
Drugs