Hemoglobinopathy 9-17-14

Question 1

*A 2 hemoglobin is increased in what condition?

Answer 1

Beta Thalasemia

Question 2

*What are sickle cell disease and Hemoglobin S/C lacking?

Answer 2

A

Question 3

Is sickle cell anemia asymptomatic or asymptomatic at birth and why?

Answer 3

Asymptomatic because Hemoglobin F is present until 6 months

Question 4

What drug shouldn’t you give a patient with Sickle cell disease?

Answer 4

Peperdine

Question 5

What kind of transfusion won’t you give a patient with Acute chest syndrome?

Answer 5

Exchange transfusion

Question 6

What is used to increase Hemoglobin F by 15%?

Answer 6

Hydroxyurea

Question 7

What population should you never transfuse if they are asymptomatic?

Answer 7

Pregnant women

Question 8

What virus will cause anemia and why?

Answer 8

Parvo-virus because they have large RBCs and are susceptible to infection

Question 9

*What percentage of HgS is found in sickle cell patients?

Answer 9

<40%

Question 10

What disease must you use PCR to identify?

Answer 10

alpha thalassemia silent

Question 11

*What percent anemia will be linked with βThal anemic at birth? (Reword question)

Answer 11

(A2>3.5)