Hemoglobin And Myoglobin Flashcards
1
Q
Which condition result from a genetic disorder with partial or total loss of one or more a(alpha) and B(beta)
A
Thalassemias
2
Q
Alpha helices are terminated by the presence if what?
A
Proline or beta-bends and loops.
3
Q
What favours the unloading of oxygen in peripheral tissues?
A
Low pH
High pCO2 (HB in increased pCO2)
Low 2,3 Bisphosphoglycerate
But low pH decreases oxygen salinity to hemoglobin
4
Q
What is bohr effect?
A
The change in binding O2
5
Q
What is thebmost abundant organic phosphate in RBC?
A
2,3 Bisphosphoglycerate
It binds deoxyhemoglobin NOT oxyhemoglobin
It stabilises the T conformation
Decreases oxygen affinity to hemoglobin
