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Gwen > Amino Acid Metabolism > Flashcards

Amino Acid Metabolism Flashcards

1
Q

Which enzyme shoes up 1,2,3 after a heart attack?

A

Creatine kinase
GOT
GPT

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2
Q

Name two different amino transferases?

A

Alanine amino transferase(ALT) aka glutamate pyruvate transaminase GPT

Aspartate aminotransferase(AST) aka glutamate oxaloacetate transaminase GOT

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3
Q

What enzyme leaks from injured heart muscles?

A

Lactate dehydrogenase

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4
Q

Qz

A
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5
Q

List three transamination reactions

A

Alanine to alpha ketoglycerate
Aspartate to alpha ketoglycerate
Alanine to pyruvate
Glutamate to alpha ketoglycerate

Amino acids to alpha keto acids

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6
Q

What is thebrate limiting reaction of urea cycle

A

Nh3 + CO2—— carbomoyl phosphate

Catalysed by: carbomoyl phosphate synthetase type 1

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7
Q

Where in urea cycle is Urea formed?

A
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8
Q

What product gives out fumarate and arginine and using what enzyme?

A

Argininesuccinate
Argininesuccinase

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9
Q

List essential and non essential amino acids

A

Non essential
.asparate
.asparagus
. Alanine
Essential
.histidine
.leucine
. Lysine
Valine

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10
Q

Aromatic amino acids

A

Tryptophan
Tyrosine
Phenylalanine

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11
Q

Pyruvate amino acids

A

Valine
Alanine
Leucine

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12
Q

Serine family

A

.Serine
.Cysteine…formed from essential methionine
.glycine

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13
Q

Glutamate family and Aspartate family (krebs cycle)

A

Glutamate
.proline
.arginine

Aspartate
.methionine
. Threonine
.Lysine

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14
Q

Where is Tyrosine formed from?

A

Essential phenylalanine

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15
Q

What is the precursor for porphyrins

A

Glycine

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16
Q

Where is creatine synthesised from?

A

Glycine
Arginine
Methionine in form of S-adenosylmethionine

17
Q

Which amino acids us glutathione synthesised from?

A

Glycine
Cysteine
Glutamate

18
Q

What gives urine a characteristic odour?

A

Phenylacetate

19
Q

What does Tyrosine give rise to?

A

Catecholamines, which includes
.dopamine
.epinephrine
.norepinephrine

20
Q

What disease is associated with low production of dopamine and what is administered?

A

Parkinsonism disease

L-dopa

21
Q

What does Glutamate decarboxylation give rise to?

A

GABA (y-aminobutyrate)
And inhibitory neurotransmitter

22
Q

What is associated with overproduction of GABA

A

Epileptic seizure

23
Q

What are GABA analogs used to treat?

A

Epilepsy
Hypertension

24
Q

Where is the neurotransmitter serotonin derived from?

A

Typtophan

25
Q

What’s the function of tagamet? A histamine receptor antagonist cemetidine.

A

Promotes duodenal ulcer healing by inhibiting secretion of gastric acids

26
Q

What is the precursor for biological synthesis of nitric oxide?

A

Arginine

27
Q

What’s the function of nitic acide (NO) in humans

A

Blood clotting, neurotransmission, control of Blood pressure

Gwen (8 decks)

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