Amino Acid Metabolism

Question 1

Which enzyme shoes up 1,2,3 after a heart attack?

Answer 1

Creatine kinase
GOT
GPT

Question 2

Name two different amino transferases?

Answer 2

Alanine amino transferase(ALT) aka glutamate pyruvate transaminase GPT

Aspartate aminotransferase(AST) aka glutamate oxaloacetate transaminase GOT

Question 3

What enzyme leaks from injured heart muscles?

Answer 3

Lactate dehydrogenase

Question 4

Qz

Question 5

List three transamination reactions

Answer 5

Alanine to alpha ketoglycerate
Aspartate to alpha ketoglycerate
Alanine to pyruvate
Glutamate to alpha ketoglycerate

Amino acids to alpha keto acids

Question 6

What is thebrate limiting reaction of urea cycle

Answer 6

Nh3 + CO2—— carbomoyl phosphate

Catalysed by: carbomoyl phosphate synthetase type 1

Question 7

Where in urea cycle is Urea formed?

Question 8

What product gives out fumarate and arginine and using what enzyme?

Answer 8

Argininesuccinate
Argininesuccinase

Question 9

List essential and non essential amino acids

Answer 9

Non essential
.asparate
.asparagus
. Alanine
Essential
.histidine
.leucine
. Lysine
Valine

Question 10

Aromatic amino acids

Answer 10

Tryptophan
Tyrosine
Phenylalanine

Question 11

Pyruvate amino acids

Answer 11

Valine
Alanine
Leucine

Question 12

Serine family

Answer 12

.Serine
.Cysteine…formed from essential methionine
.glycine

Question 13

Glutamate family and Aspartate family (krebs cycle)

Answer 13

Glutamate
.proline
.arginine

Aspartate
.methionine
. Threonine
.Lysine

Question 14

Where is Tyrosine formed from?

Answer 14

Essential phenylalanine

Question 15

What is the precursor for porphyrins

Answer 15

Glycine

Question 16

Where is creatine synthesised from?

Answer 16

Glycine
Arginine
Methionine in form of S-adenosylmethionine

Question 17

Which amino acids us glutathione synthesised from?

Answer 17

Glycine
Cysteine
Glutamate

Question 18

What gives urine a characteristic odour?

Answer 18

Phenylacetate

Question 19

What does Tyrosine give rise to?

Answer 19

Catecholamines, which includes
.dopamine
.epinephrine
.norepinephrine

Question 20

What disease is associated with low production of dopamine and what is administered?

Answer 20

Parkinsonism disease

L-dopa

Question 21

What does Glutamate decarboxylation give rise to?

Answer 21

GABA (y-aminobutyrate)
And inhibitory neurotransmitter

Question 22

What is associated with overproduction of GABA

Answer 22

Epileptic seizure

Question 23

What are GABA analogs used to treat?

Answer 23

Epilepsy
Hypertension

Question 24

Where is the neurotransmitter serotonin derived from?

Answer 24

Typtophan

Question 25

What's the function of tagamet? A histamine receptor antagonist cemetidine.

Answer 25

Promotes duodenal ulcer healing by inhibiting secretion of gastric acids

Question 26

What is the precursor for biological synthesis of nitric oxide?

Answer 26

Arginine

Question 27

What's the function of nitic acide (NO) in humans

Answer 27

Blood clotting, neurotransmission, control of Blood pressure