Glycogen Metabolism Flashcards
What are the enzymes that convert glucose to glucose 6Phospate in the the liver and muscles respectively?
Glucokinase and hexokinase
Glucose6P is converted to Glucose 1 Phosphate by?
Phosphoglucomutase.
What enzyme combines glucose 1P and UTP to form UDP glucose?
UDP glucose pyrophosphotylase
What range of carbons must be present for glycogen synthase to synthesize glycogen
7-10
What enzyme is required to start synthesizing a new glycogen molecule from scratch?
Glycogenin
What enzyme is responsible for making 1,6 glycosidic bonds in glycogen
1,4 alpha glucan branching enzyme
What hormone do Alpha cells of the pancreas produce ?
Glucagon: increase blood glucose levels during fasting
Insulin is used to reduce blood glucose levels. What cells produce insulin?
Beta cell
Note: both beta and alpha cells are called islets of Langerhans
Insulin is used to reduce blood glucose levels. What cells produce insulin?
Beta cell
Note: both beta and alpha cells are called islets of Langerhans
Is glycogen synthase activated when phosphorylated? T or F
F
Where does glycogen metabolism occur?
Cytosol and lysosomes
Function of glycogen phosphorylase?
Breaks down alpha 1,4 glycosidic bonds until there are only 4 glucose molecules left from a branch
What enzyme adds s phosphate to the liberated glucose to form Glucose 1 Phosphate?
Glycogen phosphorylase
What enzyme transfers three of the 4 glucose molecules to the main glucose chain during glycogen breakdown
Glucan tranferase
What enzyme breaks down the 1,6 alpha glycosidic bond?
Amylo alpha 1,6 glucosidase( debranching enzyme)
