Hemoglobin Flashcards
What is the primary function of hemoglobin?
To transport oxygen from the lungs to the tissues and carbon dioxide from the tissues back to the lungs.
True or False: Hemoglobin is a protein found in red blood cells.
True
What is the structural unit of hemoglobin?
Hemoglobin is composed of four polypeptide chains, typically two alpha and two beta chains.
Fill in the blank: Hemoglobin binds oxygen in the presence of _____ concentration.
high
What are the heme groups in hemoglobin responsible for?
Binding to oxygen.
Which molecule is released by hemoglobin when it delivers oxygen to tissues?
Carbon dioxide.
True or False: The affinity of hemoglobin for oxygen decreases as pH decreases.
True
What is the Bohr effect?
The physiological phenomenon where increased carbon dioxide and decreased pH reduce hemoglobin’s affinity for oxygen.
What is the normal range of hemoglobin concentration in adult males?
13.8 to 17.2 grams per deciliter.
Multiple Choice: What is the primary component of the heme group in hemoglobin? A) Iron B) Copper C) Zinc D) Magnesium
A) Iron
Fill in the blank: Hemoglobin can exist in two forms: _____ and _____.
oxyhemoglobin, deoxyhemoglobin
What condition is characterized by low levels of hemoglobin?
Anemia.
True or False: Hemoglobin can carry carbon monoxide.
True
What is methemoglobin?
A form of hemoglobin that is unable to bind oxygen due to the iron being in the ferric state.
What role does 2,3-Bisphosphoglycerate (2,3-BPG) play in hemoglobin function?
It decreases hemoglobin’s affinity for oxygen, facilitating oxygen release to tissues.
Multiple Choice: Which of the following conditions would likely increase hemoglobin levels? A) High altitude B) Anemia C) Chronic lung disease D) Hemorrhage
A) High altitude
What is the main site of hemoglobin synthesis in the body?
Bone marrow.
Fill in the blank: Hemoglobin consists of _____ heme groups.
four
What is the difference between fetal hemoglobin and adult hemoglobin?
Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin.
What is hemoglobin?
Hemoglobin is a protein in red blood cells responsible for transporting oxygen from the lungs to the rest of the body.
True or False: Hemoglobin variants are structural changes in the hemoglobin molecule.
True
What are the two main types of hemoglobin variants?
The two main types are inherited variants and acquired variants.
Fill in the blank: The most common hemoglobin variant is _____ .
Hemoglobin S
What condition is associated with Hemoglobin S?
Sickle cell disease