Hemodynamics Ballam Flashcards
the rate at which blood is pumped from the ventricles is called the
cardiac output
cardiac output =
SV X HR
CO%: Cerebral
15%
CO%: Coronary
5%
CO%: Renal
25%
CO%: Gastrointestinal
25%
CO%: Skeletal muscle
25%
CO%: skin
5%
Three main mechanisms of distributing blood to the major organ systems: 1
CO is constant, but blood flow is redistributed among the organ systems by the selective alteration of arteriolar resistance
Three main mechanisms of distributing blood to the major organ systems: 2
CO increases or decreases, but %’s remain the same
Three main mechanisms of distributing blood to the major organ systems: 3
CO is altered AND %s are altered
Stressed Volume
the volume of blood in the arteries (under high pressure)
where is the site of highest resistance to blood flow
arterioles
arterioles have what kinds of receptors that do what
alpha 1 adrenergic receptors that cause vasoconstriction. vasoconstriction increases resistance
beta adrenergic receptors
at any given moment the greatest amount of blood is contained in the
veins
unstressed volume
% of blood in the veins (!00%)
veins have ____ receptors
adrenergic receptors, causing contraction and reducing their capacitance, therefore, reducing unstressed volume
velocity of blood flow =
v = Q/ A
Q = flow ml/s A = cross sectional area (cm squared)
A = pi(r^squared), r= radius
the units of velocity are
cm/s
as vessel diameter increases, velocity
decreases, because radius in the calculation for Area is squared, so it continually gets bigger
the relationship between pressure, resistance, and flow: formula
Flow (Q) / Delta Pressure/ R
Q = P/R
the magnitude of blood flow is directly proportional to
size of pressure difference
Q = P/R
Blood flow is _____ proportional to resistance
inversely proportional
Q = P/R
TPR
total peripheral resistance
can be measured by substitution Q (flow) with CO, and the pressure difference between vena cava and aorta
SVR
systemic vascular resistance (SVR) = TPR
Poiseuille equation tells us what
the relationship between resistance, blood vessel diameter and blood viscosity
the Poiseuille equation allows us to determine the resistance of the a blood vessel to blood flow.
Poiseuille equation: formula
R = (8 * viscosity of blood * length of blood vessel)/ (radius of blood vessel raised to fourth power * pi)
What big picture relationshops of the Poiseuille equation can we talk about without seeing numbers?
direct and indirect relations, and that with each increase in the radius of the blood vessel, the numerator is reduced by fourth power of the radius
when radius increases, resistance decreases