Heme/Onc Flashcards

1
Q

What is normal range of Hgb for males?

A

14–18

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2
Q

What is the normal range of Hgb for females?

A

12–16

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3
Q

What is the normal range for Hct for males?

A

40–54

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4
Q

What is the normal range for Hct for females?

A

37-47

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5
Q

What is the normal range for serum iron?

A

50-150

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6
Q

What is normal range for serum TIBC?

A

250–450

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7
Q

What is normal range for serum platelets?

A

150–400

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8
Q

What is the treatment for pernicious anemia?

A

1000 MCG of cyanocobalamin daily for one week then monthly

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9
Q

What is the treatment for pernicious anemia?

A

1000 MCG of cyanocobalamin daily for one week then monthly

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10
Q

Which hematologic disorder is associated with the Philadelphia chromosome?

A

CML

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11
Q

After which age is CML most common?

A

CML occurs most often in persons aged 40 and older

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12
Q

Which acute leukemia is most common in adults?

A

AMP is responsible for 80% of acute leukemia in adults

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13
Q

What is the hallmark sign of ALL?

A

Pancytopenia with circulating blasts

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14
Q

What is the most common leukemia in adults?

A

CLL

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15
Q

What is the hallmark sign of CLL?

A

Lymphocytosis

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16
Q

How is non-Hodgkin’s differentiated from Hodgkin lymphoma?

A

Reed-Sternberg cells are present in Hodgkin’s lymphoma

17
Q

A sixty-year-old male is more likely to have which type of lymphoma?

A

Hodgkins as there is increased incident in the late 50s

18
Q

A thirty-year-old male is more likely to have which type of lymphoma?

A

Non-Hodgkin’s as the average age is 32

19
Q

What is the stage of lymphoma that has spread to bone?

A

Stage four involves the liver or bone marrow

20
Q

Lymphoma involving the right axilla and right groin would be classified as which stage?

A

Stage three involves the spleen or more than one lymph node group that crosses over the diaphragm

21
Q

Lymphoma involving the right neck and right axilla would be classified as which stage?

A

Stage two involves more than one lymph node group on the same side of the diaphragm

22
Q

How many lymph nodes are involved in stage one lymphoma?

A

Stage one is localized to a single lymph node or group

23
Q

Which diagnostic test is required to differentiate between ITP and SLE?

A

Bone marrow analysis

24
Q

What is the treatment for ITP and at which point is it usually indicated?

A

Treatment includes steroids and IV gamma globulin and is not indicated u til the platelet count is less than 20,000.

25
Q

What is the pervert treatment for HIV related ITP?

A

IV gamma globulin is preferred to steroids HIV related ITP

26
Q

How should HIT be treated?

A

Heparin should be discontinued and either argatroban or lepirudin should be initiated.

27
Q

What is the role of thrombin in DIC?

A

Thrombin causes conversion of a fibrin into fibrinogen, producing fibrin clots in the microcirculation leading to depletion of coagulation factors, including fibrinogen, prothrombin, platelets, factor V, and factor VIII

28
Q

What is the role of plasmin in DIC?

A

Circulating plasmin, activates fibrinolytic systems which lyses fibrin clots into fibrin degradation products.

29
Q

An HIV patient with a CD4 count of 190 should receive what prophylaxis?

A

Patients with a CD4+ cell count less than 200 cells/μL are at increased risk for opportunistic infections, most commonly those of pneumocystis, cryptosporidium, and candida. Bactrim is the correct drug to cover for PCP.

30
Q

A patient presents with a microcytic hypochromic anemia. There are decreased beta Hgb chains, normal TIBC, and normal ferritin. What kind of anemia is this?

A

Thalassemia

31
Q

A patient presents with a microcytic hypochromic anemia. Ferritin is decreased, TIBC is increased, and RDW is high. What kind of anemia is this?

A

IDA