Heme/Onc

Question 1

What is normal range of Hgb for males?

Answer 1

14–18

Question 2

What is the normal range of Hgb for females?

Answer 2

12–16

Question 3

What is the normal range for Hct for males?

Answer 3

40–54

Question 4

What is the normal range for Hct for females?

Answer 4

37-47

Question 5

What is the normal range for serum iron?

Answer 5

50-150

Question 6

What is normal range for serum TIBC?

Answer 6

250–450

Question 7

What is normal range for serum platelets?

Answer 7

150–400

Question 8

What is the treatment for pernicious anemia?

Answer 8

1000 MCG of cyanocobalamin daily for one week then monthly

Question 9

What is the treatment for pernicious anemia?

Answer 9

1000 MCG of cyanocobalamin daily for one week then monthly

Question 10

Which hematologic disorder is associated with the Philadelphia chromosome?

Answer 10

CML

Question 11

After which age is CML most common?

Answer 11

CML occurs most often in persons aged 40 and older

Question 12

Which acute leukemia is most common in adults?

Answer 12

AMP is responsible for 80% of acute leukemia in adults

Question 13

What is the hallmark sign of ALL?

Answer 13

Pancytopenia with circulating blasts

Question 14

What is the most common leukemia in adults?

Answer 14

CLL

Question 15

What is the hallmark sign of CLL?

Answer 15

Lymphocytosis

Question 16

How is non-Hodgkin’s differentiated from Hodgkin lymphoma?

Answer 16

Reed-Sternberg cells are present in Hodgkin’s lymphoma

Question 17

A sixty-year-old male is more likely to have which type of lymphoma?

Answer 17

Hodgkins as there is increased incident in the late 50s

Question 18

A thirty-year-old male is more likely to have which type of lymphoma?

Answer 18

Non-Hodgkin’s as the average age is 32

Question 19

What is the stage of lymphoma that has spread to bone?

Answer 19

Stage four involves the liver or bone marrow

Question 20

Lymphoma involving the right axilla and right groin would be classified as which stage?

Answer 20

Stage three involves the spleen or more than one lymph node group that crosses over the diaphragm

Question 21

Lymphoma involving the right neck and right axilla would be classified as which stage?

Answer 21

Stage two involves more than one lymph node group on the same side of the diaphragm

Question 22

How many lymph nodes are involved in stage one lymphoma?

Answer 22

Stage one is localized to a single lymph node or group

Question 23

Which diagnostic test is required to differentiate between ITP and SLE?

Answer 23

Bone marrow analysis

Question 24

What is the treatment for ITP and at which point is it usually indicated?

Answer 24

Treatment includes steroids and IV gamma globulin and is not indicated u til the platelet count is less than 20,000.

Question 25

What is the pervert treatment for HIV related ITP?

Answer 25

IV gamma globulin is preferred to steroids HIV related ITP

Question 26

How should HIT be treated?

Answer 26

Heparin should be discontinued and either argatroban or lepirudin should be initiated.

Question 27

What is the role of thrombin in DIC?

Answer 27

Thrombin causes conversion of a fibrin into fibrinogen, producing fibrin clots in the microcirculation leading to depletion of coagulation factors, including fibrinogen, prothrombin, platelets, factor V, and factor VIII

Question 28

What is the role of plasmin in DIC?

Answer 28

Circulating plasmin, activates fibrinolytic systems which lyses fibrin clots into fibrin degradation products.

Question 29

An HIV patient with a CD4 count of 190 should receive what prophylaxis?

Answer 29

Patients with a CD4+ cell count less than 200 cells/μL are at increased risk for opportunistic infections, most commonly those of pneumocystis, cryptosporidium, and candida. Bactrim is the correct drug to cover for PCP.

Question 30

A patient presents with a microcytic hypochromic anemia. There are decreased beta Hgb chains, normal TIBC, and normal ferritin. What kind of anemia is this?

Answer 30

Thalassemia

Question 31

A patient presents with a microcytic hypochromic anemia. Ferritin is decreased, TIBC is increased, and RDW is high. What kind of anemia is this?

Answer 31

IDA