HEMATOLOGY practice questions Flashcards
- After staining a blood smear, the RBCs appeared bluish when viewed under the microscope. The following are possible causes, except:
a. Stain or buffer is too basic
b. Inadequate rinsing
c. Inadequate buffering
d. Heparinized blood was used
b. Inadequate rinsing
- 12 RBCs with basophilic stippling were seen on a blood smear. How do report this finding?
a. Positive
b. Rare, few, moderate, many
c. 1+, 2+, 3+, 4+
d. Average number / OIO
a. Positive
- Hypochromia grading: “Area of pallor is two-thirds of cell diameter”
a. 1+
b. 2+
c. 3+
d. 4+
b. 2+
- Which of the following is an example of myeloproliferative disorder?
a. Chronic myelogous leukemia
b. Myelofibrosis with myeloid metaplasia
c. Polycythemia vera
d. All of the above
d. All of the above
+ Essential thrombocythemia – excess platelet function
- Which of the following is the hematopoietic stem cell marker:
a. CD10
b. CD34
c. CD8
d. CD56
Mixing studies
PT: increased
APTT: normal
Problem:
Problem: extrinsic pathway
Factor 7 deficiency
Mixing studies
PT: increased
APTT: increased
Problem:
Fresh plasma: Corrected
Aged Serum : Corrected
Adsorbed Plasma: not corrected
Common pathway
Factor 10
In a spun hematocrit, which blood component comes into direct contact with the sealant?
A. Plasma
B. Buffy coat
C Serum
D. Red Blood Cells
D. Red Blood Cells
Which cytochemical stain is the most useful in differentiating between CML and a leukemoid reaction?
A. Prussian blue
B. LAP
C. Peroxidase
D. Fontana stain
B. Leukocyte alkaline phospatase
- The Nitroblue tetrazolium test is used to screen for what isease?
A. Chronic Myelogenous Leukemia
B. Chronic Lymphocytic Leukemia
C. Acute Lymphoblastic Leukemia
D. Chronic Granulomatous Disease
D. Chronic Granulomatous Disease
QUEST UN #4
- Considering the inheritance pattern, which disease does not belong?
A. Homophilia A
B. Homophilia B
C. Homophilia C
D. None of the above
C. Homophilia C
- Which of the following would most likely have a blood picture showing macrocytic anemia?
A. Anemia of Chronic Disease
B. Acute blood loss
C. Sideroblastic anemia
D. Folate deficiency
D. Folate deficiency
- Which blood tube additive is preferred for blood coagulation tests?
A. Sodium fluoride
B. Sodium citrate
C. Sodium heparin
D. Potassium oxalate
B. Sodium citrate
A hemolytic anemia that shows red cells having a deficiency in both CD55 and CD59 in a flow cytogram:
A. G6PD Deficiency
C. Anemia of Chronic Disease
B. Thalassemia
D. Paroxysmal Nocturnal Hemoglobinuria
D. Paroxysmal Nocturnal Hemoglobinuria
In Bernard-Soulier Syndrome which of the following platelet functions are most likely defective?
A. Adhesion
B. Activation
C. Aggregation
D. Secretion
A. Adhesion
Which elements are most likely present in the blood smear of a patient suffering from a G6PD-Deficiency?
A. Ovalocytes and Reiter Cells
B. Bite Cells and Heinz Bodies
C. Howell-Jolly Bodies and Target Cells
D. Howell-Jolly Bodies and Basophilic Stipplings
B. Bite Cells and Heinz Bodies
Which process forms 2,3-Diphosphoglyceric acid?
A. Embden-Meyerhof Pathway
B. Rapaport-Leubering Shunt
C. Arachidonic Acid Pathway
D. Signal Transduction Pathway
B. Rapaport-Leubering Shunt
In hypochromia grading which describes a grade of 4+7
A. Thin ring of hemoglobin
B. Area of pallor is two-thirds of the cell diameter
C. Area of pallor is three-quarters of the cell diameter
D. Area of pallor is half of the cell diameter
A. Thin ring of hemoglobin
Which of the following is the most common complication of sickle cell disease in adults?
A. Acute Hemolytic Crisis
B. Acute Chest Syndrome
C. Vaso-occlusive Crisis
D. None of the above
C. Vaso-occlusive Crisis
Which blood cells are usually seen in the lesions of patients with Mycosis Fungoides?
A. Eosinophils
B. Basophils
C. B-Lymphocytes
D. T-Lymphocytes
D. T-Lymphocytes
- In Flow cytometry what does the side-angle scatter measure?
A. Cell size
B. Cell granularity
C. Cell number
D. All of the above
B. Cell granularity
- In which condition does a patient’s blood appear mauve-lavender in color?
A. Iron deficiency anemia
B. Methemoglobinemia
C. Sulfhemoglobinemia
D. Carbon monoxide poisoning
Sulfhemoglobinemia
SPICY MEDTECH REVWhich cell inclusion and RBC abnormality are consistent with G6PD Deficiency?
a. Howell-Jolly Bodies: Acanthocytes b. Cabot rings: Echinocytes
c. Heinz Bodies: Bite Cells
d. Pappenheimer bodies: Siderocytes
c. Heinz Bodies: Bite Cells
SPICY MEDTECH REVIEW
- What is the term for the removal of worn-out or damaged red cells from the circulatior
a. Lysing
b. Culling
c. Pitting
d. Splicing
b. Culling
Disintegration of a cell by a rupture of it cell wall or cell membrane
a. Lysing
b. Culling
c. Pitting
d. Splicing
a. Lysing
Removal of cytoplasmic inclusions
a. Lysing
b. Culling
c. Pitting
d. Splicing
c. Pitting
SPICY MEDTECH REVIEW
Fibrinogen is an important factor in hemostasis and is produced by the liver, Fibrinogen is a/an
a. Enzyme
b. Lipid
c. Hormone
d. Glycoprotein
d. Glycoprotein
Which of the following is considered the best site for bone marrow aspiration?
a. Posterior Iliac Crest
b. Anterior Iliac Crest
c. Femur
d. Radial bones
a. Posterior Iliac Crest
Direct Intravascular Coagulation is commonly associated with which AML according to the FAB System?
a. M5
b. M4
c. M3
d. M7
c. M3
Which of the following is not measured by the Cyanmethemoglobin method?
a. Oxyhemoglobin
b. Carboxyhemoglobin
c. Sulfhemoglobin
d. All of the above
c. Sulfhemoglobin
Which of the following best describes the Apt test?
a. Differentiate fetal and maternal blood b. Measures capillary fragility
c. Measures hemostatic ability
d. All of the above
a. Differentiate fetal and maternal blood
Screening test for theombocytopenia
a. Differentiate fetal and maternal blood b. Measures capillary fragility
c. Measures hemostatic ability
d. All of the above
b. Measures capillary fragility
Which of the following is a rare autosomal recessive bleeding disorder characterized by a deficiency in the glycoprotein Gp1b?
a. Gray Platelet Syndrome
b. May-Hegglin Anomaly
c. Wiskott-Aldrich Syndrome
d. Bernard-Soulier Syndrome
d. Bernard-Soulier Syndrome
Rare x link bleeding disorder characterized by immunodeficiency, eczema, and thrombocytopenia
a. Gray Platelet Syndrome
b. May-Hegglin Anomaly
c. Wiskott-Aldrich Syndrome
d. Bernard-Soulier Syndrome
c. Wiskott-Aldrich Syndrome
Which of the following is a rare autosomal recessive bleeding disorder characterized by the absence or reduce number of alpha granules in plateletes
a. Gray Platelet Syndrome
b. May-Hegglin Anomaly
c. Wiskott-Aldrich Syndrome
d. Bernard-Soulier Syndrome
a. Gray Platelet Syndrome
Dominant autosomal bleeding disorder and characterized by giant platelets and granulocytes having inclusions that may look like dolhe bodies
a. Gray Platelet Syndrome
b. May-Hegglin Anomaly
c. Wiskott-Aldrich Syndrome
d. Bernard-Soulier Syndrome
b. May-Hegglin Anomaly
All of the following are Supravital dyes EXCEPT;
a. Brilliant Cresyl Blue
b. New Methylene Blue
c. Bromocresol Green
d. None of the above
d. None of the above
The correct maturation order of erythrocyte mor phologic stages is:
a. Prorubricyte, rubricyte, rubriplast, metarubricyte
b. Rubriblast, prorubricyte, rubricyte, metarubricyte
c. Rubriblast, metarubricyte, rubricyte, prorubricyte
d. Rubriblast, rubricyte, prorubricyte, metarubricyte
b. Rubriblast, prorubricyte, rubricyte, metarubricyte
What anisocytes IDA is present
MICROCYTES
What is the termed used when two distinct populations of rbcs are seen
Dimorphic population
Poikilocytosis that is usually seen in disorder of lipid metabolism and severe liver disease
Acanthocytes
Poikilocytes that Shorter spines and usually seen in anemia
Echintocytes
What poikilocytosisUsually ASEEN in hereditary ELLIPITOCYTOSIS and IDA
Elliptocytea
Poikilocytosis that is ussualy seen in burns and DIC.
Thay are damaged RBCs
Schistocytes
A poikilocytosis that are ussually seen in burns and Damaged blood vessels
Produced by trauma during passage to partially obstructed blood vessel
Blister cells
Helmet cell is usually seen in?
Hemolytic anemia
Bite cell is usually seen in ?
G6PD deficiency
A distorted contracted and spicylatef RBC
Spyknocytosis
It contain Hgb S and shaped as holly leaf
Sickle cell
Sickle cell is usallu seen in
Hemoglobinopathies
An rbc without a central pallor. Nearly spherical and smaller in diameter
Spherocytes
An rbc that is ussaly seen in
Hereditary spherocytosis,
autoimmune hemolytic anemia, and
burns
Spherocytes
