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MTAP 1st day Compre Reviewer > HEMATOLOGY practice questions > Flashcards

HEMATOLOGY practice questions Flashcards

1
Q
  1. After staining a blood smear, the RBCs appeared bluish when viewed under the microscope. The following are possible causes, except:​
    ​
    a. Stain or buffer is too basic​
    b. Inadequate rinsing​
    c. Inadequate buffering​
    d. Heparinized blood was used
A

b. Inadequate rinsing

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2
Q
  1. 12 RBCs with basophilic stippling were seen on a blood smear. How do report this finding?​​

a. Positive​
b. Rare, few, moderate, many​
c. 1+, 2+, 3+, 4+​
d. Average number / OIO​

A

a. Positive

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3
Q
  1. Hypochromia grading: “Area of pallor is two-thirds of cell diameter”​

a. 1+​
b. 2+​
c. 3+​
d. 4+ ​
​

A

b. 2+

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4
Q
  1. Which of the following is an example of myeloproliferative disorder?​
    ​
    a. Chronic myelogous leukemia​
    b. Myelofibrosis with myeloid metaplasia​
    c. Polycythemia vera​
    d. All of the above ​
A

d. All of the above ​
+ Essential thrombocythemia – excess platelet function

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5
Q
  1. Which of the following is the hematopoietic stem cell marker:​
    ​
    a. CD10​
    b. CD34​
    c. CD8​
    d. CD56
A
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6
Q

Mixing studies
PT: increased
APTT: normal
Problem:

A

Problem: extrinsic pathway
Factor 7 deficiency

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7
Q

Mixing studies
PT: increased
APTT: increased
Problem:

Fresh plasma: Corrected
Aged Serum : Corrected
Adsorbed Plasma: not corrected

A

Common pathway
Factor 10

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8
Q

In a spun hematocrit, which blood component comes into direct contact with the sealant?

A. Plasma
B. Buffy coat
C Serum
D. Red Blood Cells

A

D. Red Blood Cells

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9
Q

Which cytochemical stain is the most useful in differentiating between CML and a leukemoid reaction?

A. Prussian blue
B. LAP
C. Peroxidase
D. Fontana stain

A

B. Leukocyte alkaline phospatase

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10
Q
  1. The Nitroblue tetrazolium test is used to screen for what isease?

A. Chronic Myelogenous Leukemia

B. Chronic Lymphocytic Leukemia

C. Acute Lymphoblastic Leukemia

D. Chronic Granulomatous Disease

A

D. Chronic Granulomatous Disease

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11
Q

QUEST UN #4

  1. Considering the inheritance pattern, which disease does not belong?

A. Homophilia A

B. Homophilia B

C. Homophilia C

D. None of the above

A

C. Homophilia C

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12
Q
  1. Which of the following would most likely have a blood picture showing macrocytic anemia?

A. Anemia of Chronic Disease

B. Acute blood loss

C. Sideroblastic anemia

D. Folate deficiency

A

D. Folate deficiency

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13
Q
  1. Which blood tube additive is preferred for blood coagulation tests?

A. Sodium fluoride

B. Sodium citrate

C. Sodium heparin

D. Potassium oxalate

A

B. Sodium citrate

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14
Q

A hemolytic anemia that shows red cells having a deficiency in both CD55 and CD59 in a flow cytogram:

A. G6PD Deficiency

C. Anemia of Chronic Disease

B. Thalassemia

D. Paroxysmal Nocturnal Hemoglobinuria

A

D. Paroxysmal Nocturnal Hemoglobinuria

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15
Q

In Bernard-Soulier Syndrome which of the following platelet functions are most likely defective?

A. Adhesion

B. Activation

C. Aggregation

D. Secretion

A

A. Adhesion

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16
Q

Which elements are most likely present in the blood smear of a patient suffering from a G6PD-Deficiency?

A. Ovalocytes and Reiter Cells

B. Bite Cells and Heinz Bodies

C. Howell-Jolly Bodies and Target Cells

D. Howell-Jolly Bodies and Basophilic Stipplings

A

B. Bite Cells and Heinz Bodies

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17
Q

Which process forms 2,3-Diphosphoglyceric acid?

A. Embden-Meyerhof Pathway

B. Rapaport-Leubering Shunt

C. Arachidonic Acid Pathway

D. Signal Transduction Pathway

A

B. Rapaport-Leubering Shunt

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18
Q

In hypochromia grading which describes a grade of 4+7

A. Thin ring of hemoglobin

B. Area of pallor is two-thirds of the cell diameter

C. Area of pallor is three-quarters of the cell diameter

D. Area of pallor is half of the cell diameter

A

A. Thin ring of hemoglobin

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19
Q

Which of the following is the most common complication of sickle cell disease in adults?

A. Acute Hemolytic Crisis

B. Acute Chest Syndrome

C. Vaso-occlusive Crisis

D. None of the above

A

C. Vaso-occlusive Crisis

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20
Q

Which blood cells are usually seen in the lesions of patients with Mycosis Fungoides?

A. Eosinophils

B. Basophils

C. B-Lymphocytes

D. T-Lymphocytes

A

D. T-Lymphocytes

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21
Q
  1. In Flow cytometry what does the side-angle scatter measure?

A. Cell size

B. Cell granularity

C. Cell number

D. All of the above

A

B. Cell granularity

22
Q
  1. In which condition does a patient’s blood appear mauve-lavender in color?

A. Iron deficiency anemia

B. Methemoglobinemia

C. Sulfhemoglobinemia

D. Carbon monoxide poisoning

A

Sulfhemoglobinemia

23
Q

SPICY MEDTECH REVWhich cell inclusion and RBC abnormality are consistent with G6PD Deficiency?

a. Howell-Jolly Bodies: Acanthocytes b. Cabot rings: Echinocytes

c. Heinz Bodies: Bite Cells

d. Pappenheimer bodies: Siderocytes

A

c. Heinz Bodies: Bite Cells

24
Q

SPICY MEDTECH REVIEW

  1. What is the term for the removal of worn-out or damaged red cells from the circulatior

a. Lysing

b. Culling

c. Pitting

d. Splicing

A

b. Culling

25
Q

Disintegration of a cell by a rupture of it cell wall or cell membrane

a. Lysing

b. Culling

c. Pitting

d. Splicing

A

a. Lysing

26
Q

Removal of cytoplasmic inclusions

a. Lysing

b. Culling

c. Pitting

d. Splicing

A

c. Pitting

27
Q

SPICY MEDTECH REVIEW

Fibrinogen is an important factor in hemostasis and is produced by the liver, Fibrinogen is a/an

a. Enzyme

b. Lipid

c. Hormone

d. Glycoprotein

A

d. Glycoprotein

28
Q

Which of the following is considered the best site for bone marrow aspiration?

a. Posterior Iliac Crest

b. Anterior Iliac Crest

c. Femur

d. Radial bones

A

a. Posterior Iliac Crest

29
Q

Direct Intravascular Coagulation is commonly associated with which AML according to the FAB System?

a. M5

b. M4

c. M3

d. M7

A

c. M3

30
Q

Which of the following is not measured by the Cyanmethemoglobin method?

a. Oxyhemoglobin

b. Carboxyhemoglobin

c. Sulfhemoglobin

d. All of the above

A

c. Sulfhemoglobin

31
Q

Which of the following best describes the Apt test?

a. Differentiate fetal and maternal blood b. Measures capillary fragility
c. Measures hemostatic ability
d. All of the above

A

a. Differentiate fetal and maternal blood

32
Q

Screening test for theombocytopenia

a. Differentiate fetal and maternal blood b. Measures capillary fragility
c. Measures hemostatic ability
d. All of the above

A

b. Measures capillary fragility

33
Q

Which of the following is a rare autosomal recessive bleeding disorder characterized by a deficiency in the glycoprotein Gp1b?

a. Gray Platelet Syndrome

b. May-Hegglin Anomaly

c. Wiskott-Aldrich Syndrome

d. Bernard-Soulier Syndrome

A

d. Bernard-Soulier Syndrome

34
Q

Rare x link bleeding disorder characterized by immunodeficiency, eczema, and thrombocytopenia

a. Gray Platelet Syndrome

b. May-Hegglin Anomaly

c. Wiskott-Aldrich Syndrome

d. Bernard-Soulier Syndrome

A

c. Wiskott-Aldrich Syndrome

35
Q

Which of the following is a rare autosomal recessive bleeding disorder characterized by the absence or reduce number of alpha granules in plateletes

a. Gray Platelet Syndrome

b. May-Hegglin Anomaly

c. Wiskott-Aldrich Syndrome

d. Bernard-Soulier Syndrome

A

a. Gray Platelet Syndrome

36
Q

Dominant autosomal bleeding disorder and characterized by giant platelets and granulocytes having inclusions that may look like dolhe bodies

a. Gray Platelet Syndrome

b. May-Hegglin Anomaly

c. Wiskott-Aldrich Syndrome

d. Bernard-Soulier Syndrome

A

b. May-Hegglin Anomaly

37
Q

All of the following are Supravital dyes EXCEPT;

a. Brilliant Cresyl Blue

b. New Methylene Blue

c. Bromocresol Green

d. None of the above

A

d. None of the above

38
Q

The correct maturation order of erythrocyte mor phologic stages is:

a. Prorubricyte, rubricyte, rubriplast, metarubricyte

b. Rubriblast, prorubricyte, rubricyte, metarubricyte

c. Rubriblast, metarubricyte, rubricyte, prorubricyte

d. Rubriblast, rubricyte, prorubricyte, metarubricyte

A

b. Rubriblast, prorubricyte, rubricyte, metarubricyte

39
Q

What anisocytes IDA is present

A

MICROCYTES

40
Q

What is the termed used when two distinct populations of rbcs are seen

A

Dimorphic population

41
Q

Poikilocytosis that is usually seen in disorder of lipid metabolism and severe liver disease

A

Acanthocytes

42
Q

Poikilocytes that Shorter spines and usually seen in anemia

A

Echintocytes

43
Q

What poikilocytosisUsually ASEEN in hereditary ELLIPITOCYTOSIS and IDA

A

Elliptocytea

44
Q

Poikilocytosis that is ussualy seen in burns and DIC.

Thay are damaged RBCs

A

Schistocytes

45
Q

A poikilocytosis that are ussually seen in burns and Damaged blood vessels

Produced by trauma during passage to partially obstructed blood vessel

A

Blister cells

46
Q

Helmet cell is usually seen in?

A

Hemolytic anemia

47
Q

Bite cell is usually seen in ?

A

G6PD deficiency

48
Q

A distorted contracted and spicylatef RBC

A

Spyknocytosis

49
Q

It contain Hgb S and shaped as holly leaf

A

Sickle cell

50
Q

Sickle cell is usallu seen in

A

Hemoglobinopathies

51
Q

An rbc without a central pallor. Nearly spherical and smaller in diameter

A

Spherocytes

52
Q

An rbc that is ussaly seen in

Hereditary spherocytosis,

autoimmune hemolytic anemia, and

burns

A

Spherocytes

MTAP 1st day Compre Reviewer (10 decks)

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