Hematology cell types Flashcards
Burr Cells (Enchinocytes)
Uremia, Hypomag., hypophos, HUS
Hypersegmented Neutrophils
Megoblastic Anemia (Folic Acid/B12)
Schistocytes
TTP, DIC
Auer Rods
AML
Codocytes (Target Cells)
B-Thalassemia
JAK-2
Polycythema Vera (increase in x3 myeloid lines)
Downey Cells
Infectious Mono., EBV, cytomegalovirus
Koilonychia
Fe+ def. anemia (spoon shaped nails)
Philadelphia Chromosome
CML
Howell-Jolly Bodies
Damaged spleen - Hereditary spherocytosis (Dx w/ with osmotic fragility test)
Heinz Bodies
G6PD def., uremia
Rouleaux formation
Multiple Myeloma, Waldenstrom’s
Smudge Cells
CLL
Reed-Sternberg (Owl eyes)
Hodgkin’s Lymphoma and Minimal Change DZ
Basophilic Stippling
B-Thalassemia, lead poisoning, megaloblastic anemia
Bence-Jones proteins
Multiple Myeloma
low hematocrit with reticulocytosis
Damaged spleen - Howell-Jolly bodies
Direct Coombs test
Detects antibodies for RBC’s in autoimmune hemolytic anemia
Indirect Coombs test
Detect antibodies for RBC’s in pregnant women (Rh)
Treated with phototherapy in neonatal period
Hereditary spherocytosis
Restrict activity that might cause trauma
ITP, EBV, damage to spleen
Chocolate colored blood
Methmoglobinemia Tx with Methylene blue
hydroxyurea
Tx for Sickle pain prevention. Increases HbF
Decreased haptoglobin
G6PD def. and hereditary spherocytosis
prolonged bleeding time, low platelet count, and increased PT and PTT.
DIC and Protein C
Recurrent DVTs
Factor V Leiden
left-shifted myeloid series in middle-aged patients, causing fatigue, night sweats, and low-grade fevers
CML
BLASTS
Think of a leukemia