Hematology Flashcards
anemia, microcytic, with neuro sx?
lead poisoning
anemia macrocytic with neuro sx?
B12 deficiency
anemia in a patient who eats ice?
iron defn
anemia that develops after taking sulfa drug?
G6PD defn
anemia in patient with RA?
chronic disease
7 year old with dark urine and jaundice. 1 week of abd pain, vomiting, diarrhea with blood. petechiae on extremities. anemic, thrombocytopenic. schistocytes on smear. dx?
HUS
cause of HUS?
e coli O157:H7
patient with DVT, burning pain in hands with redness. Warm baths cause itching. elevated Hgb. low EPO. all else negative. dx?
polycythemia vera
tx of polycythemia vera?
phlebotomy
hydroxyurea
low dose aspirin
antihistamine
patient with fatigue post UTI tx. CBC shows normocytic anemia, heinz bodies and degmacytes (bite cells). Dx?
G6PD deficiency
Drugs that provoke anemia in G6PD deficiency?
antimalarials nitrofurantoin sulfa dapsone inh ibuprofen high dose aspirin fava beans
66 year old with punched out lesions in hips, femurs, vert, pathologic fx, back pain, weakness, fatigue. Labs show anemia, hypercalcemia, increased BUN and Cr. Dx? testing?
multiple myeloma
SPEP - monoclonical antibody spike UPEP - bence jones protein - bone marrow biopsy
young patient with recurrent gum bleeding. 2 epistaxis. rash on ankles and legs. healthy appearing with petechiae. HSM. labs show platelet of 40,000. PT and PTT normal. Dx? tx?
ITP
no tx if asymptomatic
- can give platelets, glucocorticoids, IVIG, splenectomy
48 year old with pallor and fatigue, no bleeding. See hypochromic microcytic anemia. Hgb 9.4 and iron normal. Next step? Dx?
hgb electrophoresis
thalassemia
young woman with prolonged bleeding, easy bruiser, easy bleeding, heavy menstrual cycles. Lab shows normal platelet count, normal PT, increased PTT. Bleeding time is elevated. Dx? Tx?
von willebrand disease
desmopressin
