GI Flashcards
serology for UC
p ANCA
treatment of UC
5- ASA (mesalamine)
steroids
immunosuppression
anti-TNFalpha
in a patient with acute hepatitis, what type of bilirubin would you expect to be elevated?
direct (conjugated) bilirubin
Colon biopsy for crohn’s disease shows?
transmural inflammation
non caseating granulomas
cobblestoning
skip lesions
tx of IBS
behavioral
avoid gas diet gluten free high fiber exercise
patient has elevated iron and ferritin, increased transferrin, decreased TIBC with type 2 DM and cirrhosis. Diagnosis?
hereditoary hemochromotisis
diagnostic test for hereditary hemochromotosis?
genetic test HFE gene
tx of hereditary hemochromatosis?
phlebotomy
what stress ulcer prophylaxis tx causes c diff?
PPI, h2 blocker
initial test for patient with epigastric pain, nausea, and vomiting?
serum lipase for pancreatitis
what lab test on ascites fluid would confirm diagnosis of cirrhosis?
serum-ascites albumin gradient
(SAAG) > 1.1
study to confirm diagnosis of achalasia?
barium esophagram, then esophageal manometry
treatment of achalasia?
esophageal dilation
surgical myometry
botulinum toxin
medical - nifedipine, nitrates
37 year old man with pruritus and RUQ abd pain. history of UC. Mild jaundice. ELevated direct bili and alk phosph. Dx?
PRIMARY sclerosing cholangitis
labs associated with primary sclerosing cholangitis? what testing?
p ANCA
ERCP shows beads of biliary system
tx for primary sclerosing cholangitis?
no medical tx
ERCP for dominant stricture\
liver transplant
malignancies patient at risk for with primary sclerosing cholangitis?
cholangiocarcinoma, gb cancer, hepatocellular carcinoma
56 year old man, nonsmoker, comes in with SOB, wheezing, cough. XR shows COPD/emphysema. Labs show elevated ALT/AST and signs of cirrhosis. Dx?
alpha 1 antitrypsin deficiency
tx of alpha 1 antitrypsin defn?
infusion of alpha 1 antitrypsin
liver transplant
middle aged female with pruritus and fatigue, autoimmune disorder, hyperpigmented skin without jaundice. Minimally elevated AST/ALT, elevated alk phosph, normal bili. Dx?
primary biliary cirrhosis
dx to confirm primary biliary cirrhosis?
liver biopsy
lab test that confirms primary biliary cirrhosis or suggests PBC?
+ AMA
tx of primary biliary cirrhosis
ursodeoxycholic acid
20 year old woman, elevated AST/ALT. No hep B/hep C. non drinker. ferritin normal. ceruloplasmin decreased. Dx?
wilson’s disease
test to confirm wilson’s disease?
low serum copper
kayser fleischer rings
liver biopsy
genetic testing
tx of wilson’s disease?
copper chelation
- penicillamine/trientein
