Hematology #3 Flashcards
Transfusion reaction: Hemolytic Onset and treatment
Onset: Shortly after transfusion
Treatment: stop transfusion, supportive care
Transfusion reaction: Anaphylactic Pathology and S/S
Pathology: Hypersensitivity
S/S: Urticaria, dyspnea, wheezing
Transfusion reaction: anaphylaxis
Onset and treatment
Onset: within 30 minutes of transfusion
Treatment: stops transfusion, Epi, steroids
Transfusion reaction: Febrile
Pathology and S/S
Pathology: antibodies and leukocytes
S/S: fever, chills
Transfusion reaction: Febrile
onset and treatment
Onset: 30-90 minutes
Treatment: stop transfusion
Transfusion reaction: Circulatory overload
Pathology and S/S
Pathology: circulatory collapse
S/s: couch, cyanosis
Transfusion reaction: circulatory overload
Onset and treatment
Onset: anytime
Treatment: stop transfusion, Lasix
Transfusion reaction: Hemolytic pathology & s/s
Pathology: ABO incompatibility
S/S: Fever, chills, dyspnea and back pain
Patient blood type who is the most likely to develop a hemolytic reaction.
Type O blood
Can only receive type O
What percentage of hemolytic reactions will develop DIC?
30-50%
Hemolytic reaction treatments
Support hemodynamics with fluid and pressers
Maintain renal perfusion and function with fluid and diuretics
Prevention of DIC mainly with pressure support and oxygenation
Circulatory overload
Blood is colloidal, draws fluid into vascular spac
Indications for FFP
Coumadin therapy reversal, DIC, Antithrombin III deficiency (extended heparin tx), dilutional coagulopathy (>1 blood volume or 10 units PRBC’s)
Ratio given with PRBCs
1:4 until 10 units PRBCs then 1:1
Dosing for coagulation driven by coags
Pt/PTT >1.5 - 1.8 normal
