Hema Retake Flashcards

1
Q

Total blood volume in an adult

A

5-6 liters

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2
Q

Micro sample collection only applies to infants, young children, adult with poor veins

A

should not be used on adult

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3
Q

Used in ESR

A

3.8% sodium citrate

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4
Q

Produces a bluish background on blood smear when stained with Wright’s or Leishman’s stain

A

Heparin

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5
Q

Most reliable criteria for estimation of cell lineage

A

Pattern of nuclear chromatin

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6
Q

Ability of the lens to delineate detail in a specimen

A

Resolution

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7
Q

Counting chamber for standardization of vaccine

A

Petroff-Hausser

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8
Q

Counting chamber for eosinophil and basophil

A

Fuchs-Rosenthal

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9
Q

Diluting fluid used for spectrophotometry

A

Gower’s Fluid

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10
Q

Used in cases of emergency when no other diluting fluids are available

A

NSS

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11
Q

Bone marrow cellularity

A

Aspiration

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12
Q

Multi-lineage cytokine

A

IL-1

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13
Q

earliest recognizable erythrocytic lineage

A

Rubriblast

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14
Q

start of Hb formation

A

Prorubricyte

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15
Q

last stage capable of cell division

A

Rubricyte

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16
Q

last stage with nucleus

A

Metarubricyte

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17
Q

stage that is normally seen in the peripheral blood

A

Reticulocyte

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18
Q

index of effective erythropoiesis

A

Reticulocyte count

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19
Q

RPI more than or equal to 3

A

evidence of hemolytic anemia

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20
Q

Generation of ATP

A

Embden-Meyerhof Pathway

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21
Q

Production of 2,3 DPG that affects the affinity of hemoglobin to oxygen

A

Leubering-Rapoport Pathway

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22
Q

Variation of Hb content

A

Anisochromasia

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23
Q

Seen in alcoholic cirrhosis, abetalipoproteinemia, post-splenectomy, PK deficiency, & LCAT deficiency

A

Spurr cell (Acanthocyte)

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24
Q

PK deficiency

A

Echinocyte

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25
Q

G6PD

A

Degmacyte (bite cell)

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26
Q

IDA

A

Elliptocyte (cigar)

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27
Q

Sickle cell anemia

A

Drepanocyte

28
Q

Scattered inclusion that appears homogeneously

A

Basophilic stipplings

29
Q

DNA mitotic spindle remnant of microtubules

A

Cabot ring

30
Q

Flat, blue-gray pieces, often in groups of four

A

Papenheimer bodies

31
Q

Small, dense, round inclusion, single or multiple

A

Howell-Jolly Bodies

32
Q

Predominant Hb in fetal life

A

Hb F

33
Q

zero degree

A

cell size

34
Q

10 degree

A

Cell structure

35
Q

90 degree

A

lobularity

36
Q

bacterial infection

A

Neutrophil

37
Q

allergy

A

Basophil

38
Q

macrophage precursor

A

Monocyte

39
Q

parasite infection

A

Eosinophil

40
Q

antibody

A

Lymphocyte

41
Q

not included in the extramedullary hematopoiesis (meaning its the formation of blood cells outside the bone marrow)

A

Bone marrow

42
Q

decreased serum iron and increased TIBC

A

Iron Deficiency Anemia

43
Q

valine replaces glutamic acid at the 6th amino acid on beta chain

A

Hemoglobin S

44
Q

increased ESR

A

Titling of tube

45
Q

Enzyme that is most likely to elicit hemolytic anemia

A

PK (pyruvate kinase)

46
Q

Sucrose lysis positive

A

PNH (paroxysmal nocturnal hemoglobinuria)

47
Q

Not directly determined in an automated analyzer

A

Hematocrit

48
Q

Dense azurophilic granulation in all WBCs except neutrophils, associated with gargoylism

A

Alder Reilly Anomaly

49
Q

Irregular size inclusion bodies similar to Dohle-amato bodies, autosomal disorder with presence of inclusion in PMN and monocyte with a giant PLT and low PLT count or thrombocytopenia

A

May-Hegglin Anomaly

50
Q

Failure of the nucleus of the neutrophils to lobulate or segment something pince-nez

A

Pelger-Huet

51
Q

Recurrent chronic inability of neutrophil to kill ingested bacteria that cannot make hydrogen peroxide

A

Chronic Granulomatous Disease

52
Q

Characterized by the presence of peroxidase positive granules and inclusion which appear to be abnormal lysosomes

A

Chediak Higashi

53
Q

Least seen in peripheral blood

A

Basophil

54
Q

Best estimation of wbc count in blood smear

A

Absolute count

55
Q

Best source: active morrow mag aspirate 20 yr old patient

A

Iliac crest

56
Q

Anemia of renal failure causes

A

Decrease production of erythropoiesis

57
Q

MCV= 76 MCH= 26 MCHC= 27

A

Microcytic, Normochromic

58
Q

Absence or deficiency of one globin chain

A

Thalassemia

59
Q

Patients undergoing cancer chemotherapy

A

Myelophthisic anemia

60
Q

Deficiency causes niemann’s pick disease

A

Sphingomyelinase

61
Q

Why is there a need to correct wbc for NRBC?

A

NRBC can be miscount as WBC due to appearance

62
Q

Excess iron in an erythroblast

A

Sideroblast

63
Q

What can cause anemia associated with neurological symptoms?

A

Vitamin B12 deficiency

64
Q

No neurologic manifestations

A

Folic Acid Deficiency

65
Q

Failure of erythroid something

A

Pure red cell aplasia