Clinical Chemistry Flashcards

1
Q
  1. Which of the following scenarios is/are NOT considered as a correct way to identify a patient?
    I. “Are you Yelan?”, phlebotomist Topaz asked.
    II. Cyno asks the nurse in charge the name of an unconscious patient and at the same time checks the ID band on the patient’s wrist
    III. “May I ask for your name, Sir?”. “I’m Bronya.”
    IV. Kafka looks at the patient, then the requisition slip, then proceeds to blood extraction.
A

a. I, II, IV

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2
Q

Laboratories should monitor and track pre-analytical indicators of quality to develop strategies to identity root causes of error and develop counter measures. Examples of pre-analytical quality indicators include:

A

d. Rate of an inaccurate test order entry into the
laboratory information system

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3
Q

How will you correct this venipuncture error?

A

Slowly pull the needle backwards until blood flow
resumes.

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4
Q

Which of the following should be avoided when extracting blood?
I. avoid areas with hematoma
II. extract above the IV line
III. extract from an area on the opposite side of the mastectomy
IV. draw blood from a standing patient

A

-II, IV

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5
Q

Which of the following statements incorrectly describes the procedure for specimen labeling?

A

Labelling could be done before collection

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5
Q

After a difficult venipuncture requiring prolonged application of the tourniquet, the serum potassium was found to be 6.8 mEg/L (6.8 mmol/L). The best course of actions is to:

A

Repeat the test using freshly drawn serum

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6
Q

In a specimen collected for plasma glucose analysis, sodium fluoride,

A

Inhibits glycolysis

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7
Q

The preparation of a patient for standard glucose tolerance testing should include:

A

A high carbohydrate diet for 3 days

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8
Q

A healthy person with a blood glucose of 80 mg/Dl (4.4 mmol/L) would have a simultaneously determined cerebrospinal fluid value of:

A

50 mg/dL (2.3 mmol/L)

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9
Q

Which one of the following values obtained during a glucose tolerance test are diagnostic of diabetes mellitus?

A

Fasting plasma glucose = 126 mg/dL (6.9 mmol/L)

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10
Q

In protein electrophoresis, when the sample is placed in an electric field connected to a buffer of 8.6, all of the proteins:

A

Have a negative charge

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11
Q

The above serum protein electrophoresis pattern is consistent with:

A

Chronic Inflammation

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12
Q

In familial hypercholesterolemia, the hallmark finding is an elevation of

A

Low-density lipoproteins

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13
Q

A 13-year old girl with hyperlipoproteinemia and lipase deficiency has the following lipid profile: Cholesterol :300 mg/dL
LDL: increased
HDI:decreased
Triglycerides: 200 mg/dL
Chylomicrons: present
A serum specimen from this patient that was refrigerated overnight would most likely be:

A

Creamy layer over cloudy serum

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14
Q

Transportation of 60-75% of plasma cholesterol is performed by:

A

Low-density lipoproteins

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15
Q

Which of the following statements is true regarding the coefficient of variation (CV)?

A

It is the percentile expression of the mean

16
Q

What Westgard rule has been violated in the Levey-Jennings chart pictured above?

A

4:1s; four consecutive values exceed the +1SD or -
1SD limit; indicates systematic error.

17
Q

in the Gaussian distribution curve, 68% of the values should be:

A

Within +/- 1SD

18
Q
  1. An automated method for measuring chloride which generates silver ions in the reaction is:
A

Coulorometry

19
Q

Laboratory HBD’s blood gas instrument is out-of- control for all parameters. What would be the first procedure to be followed?

A

Recalibrate, then repeat control

20
Q

The osmolality of a serum urine specimen is measured by a change in the:

A

Osmotic pressure

21
Q

Stray light can be detected in a spectrophotometer by using a:

A

Sharp cut off filter

22
Q

Which of the following statements about normality is TRUE?

A

Normality is based on the same principle of molarity except molarity is based on GMW Gram molecular weight) and normality is based on GEW (gram equivalent weight)

23
Q

Calculate the molarity of 0.365g of pure HCI gas dissolved in 50 mL of solution.

A

0.2M