hema one Flashcards
1
Q
- Anemia can be caused by chronic blood loss or acute blood loss
A
both
2
Q
- A Classification of anemia, or MCV, is > 90 fl but MCHC is normal
A
Macrocytic normochromic anemia
3
Q
- Impaired release of storage iron associated with increased HEPCIDIN LEVEL
A
Anemia of chronic disease
4
Q
- Caused by block in the protoporphyrin pathway resulting in defective hemoglobin synthesis and iron overload
A
Sideroblastic anemia
5
Q
- Anemia with normocytic normochromic anemia, by characteristics cause of basophilic stippling
A
Seen in lead poisoning
6
Q
- A falsely elevated hematocrit is obtained, which of the following calculated values will not be affected.
A
MCH
7
Q
- Which of these types of anemia are under the category of impaired production
A
Iron deficiency, sideroblastic anemia, anemia of chronic inflammations. All of the choices are types of anemia are impaired types of anemia
8
Q
- The RBC indices obtained in the patient are as follows:
MCV: 88 fl
MCH: 30 pg
MCHC: 34%
Rbc on the pbs would appear:
A
Normocytic normochromic anemia
9
Q
- (DATA TABLE) in an uncomplicated cases of severe iron deficiency anemia which of the following sets shows typical pattern of results
A
Decrease rbc, hemoglobin, mcv, mch, mchc, serum iron, serum ferritin, percent saturation, bone marrow iron stores, RDW distribution width and TIBC and serum soluble transferrin receptors are increased
10
Q
- What is the first type of cell that is produced by the developing embryo
A
Erythrocytes
11
Q
- As most blood cells lines matures, which of the following is the characteristics
A
Nucleus to cytoplasm ratio decreases N:C decrease
12
Q
- DAT is open positive
A
Acquired hemolytic anemia
13
Q
- Anemia of chronic infection is characterized by:
A
Decrease Serum iron levels
14
Q
- A patient is admitted with a history of chronic bleeding secondary to peptic ulcer, hematology workup reveals severe microcytic hypochromic anemia. Iron studies are requested: which of the following will be expected
A
Decrease serum iron, increase TIBC, decrease storage iron
15
Q
- Which of the set of laboratory findings is consistent with hemolytic anemia
A
Decrease in erythrocyte survival, increase of catabolism of protein content of heme
16
Q
- Chronic blood loss can lead to
A
Gradual loss of blood, Lead to loss of iron leading to iron deficiency anemia
17
Q
- Many microspherocytes, schistocytes, budding off of spherocytes can be seen in PBS with:
A
Extensive burns
18
Q
- A beta lipoproteinemia is characterized by malt anemia and numerous
A
Acanthocytes in PBS
19
Q
- Most common cause of iron deficiency
A
Bleeding
20
Q
- Ineffective erythropoiesis is due to the following except:
A
Iron deficiency anemia
21
Q
- These red blood cell parameter is increased in iron deficiency anemia.
A
TIBC
22
Q
- If there is defective glucose 6 phosphate dehydrogenase in red cells. The cause of hemolysis is:
A
Hemolysis of intrinsic
23
Q
- In chronic posthemorrhagic anemia, which is not true
A
Reticulocyte count is very low
24
Q
- Isoimmune hemolytic disease of the newborn is
A
Due to ABO incompatibility
25
25. In aplastic anemias the marrow cellularity is usually
Decreased
26
26. Rh null disease person shows morphological changes in red cell while person with rh negative conditions possess CDE antigens
The first statement is true, second statement is false
27
27. Acanthocytes and echinocytes can be differentiated based on the following:
All of the above
28
28. The opposite of aplastic anemia (no or few production)
Polycythemia
29
29. Extrinsic hemolytic anemia is caused by:
All of the choices
Due to physical agents, Hidden trauma, vegetable animal poison, infectious agents like malarial parasites and bacteria
30
30. Defect of rbc itself usually hereditary are grouped and group as membrane, metabolic or hemoglobin defects
Intrinsic hemolytic anemia
31
31. Anemia most commonly present in which of the following symptoms
Shortness of breath and fatigue Note: Because of the lack of oxygen supply
32
32. Which of the following conditions can be differential diagnosis of anemic adult patient with
MCV of 125 fl
RDW: 20 %
Reference is 11.5-14.5%
Vit.b12 deficiency
33
33. Schistocytes, ovalocytes, acanthocytes are example of abnormal changes in:
Shape
34
34. Which of the following is detectable only in the examination of PBS.
poikilocytosis
35
35. Which of the following conditions are considered anemic with hemoglobin value of 14.5 g/dl
Newborn
36
36. What are the initial lab test for diagnosis of anemia:
CBC, reticulocyte count, PBS
37
37. An increase in which of the following suggest a shortened lifespan of rbc in hemolytic anemia
Increase of reticulocyte, Reticulocyte count
38
38. An autoimmune reaction destroys hematopoietic stem cells in the bone marrow of a young adult patient. Amount of active bone marrow including erythroid precursors is diminished. Erythroid precursors that are present are normal in appearance but are too few to meet the demand of circulating red cells and anemia develops, reticulocyte count is low. the mechanism of anemia would be described as:
Insufficient erythropoiesis
39
39. Which of the following are important to consider a patient's history when investigating the cause of anemia
All of the above
Diet and medication, occupation hobbies and travel, bleeding episodes in his/her family members, genetics
40
40. To determine which of the following conditions would be included in the differential diagnosis of anemic adult patient with absolute reticulocyte count of 20x10^9/L MCV of 65fl
Iron deficiency anemia
