Helminth/Protozoa stuff Flashcards

1
Q

Helminths- how do you dx

A

eggs in stool

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2
Q

Types of Helminths

A

Nematodes- tissue invading and non
Cestodes
Trematodes

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3
Q

Nematodes- tx

A

Mebendazole

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4
Q

Enterobius

A

Perianal pruritis
Retroinfections
Dx with w/ scotch tape

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5
Q

Necator/Ancylostoma

A

PENETRATES SKIN
skin –> hematogenous –> lung –> cough –> small intestine
Mature sucks blood –> Fe deficiency anemia
also causes- pruritis, cough, and pulmonary infiltrate
only infects in warm weather
transplacental

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6
Q

Ascaris lumbricoides

A

Eat the larvae –> SI –> hematogenous –> lung
Loefflers syndrome- pulmonary eosinophilia
can also cause- INTESTINAL OBSTRUCTION, malnutrition, invades bile duct and appendix

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7
Q

Trichurius Trichiura

A

RECTAL PROLAPSE
dif versions for dif animal species
females cause the dz

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8
Q

Strongyloides

A

PENETRATE SKIN
skin –> hematogenous –> lung –> cough –> SI
LARVAE CURRENS
also cause- enteritis, malabsorption bronchopneumonia
hemoptysis

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9
Q

Why should you not give corticosteroids for Strongyloides

A

Strongyloides has free living form that is commensural with gram negative bacteria, so corticosteroids promote bacteremia

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10
Q

Tissue invading nematodes

A

Trichenella Spiralis
Anisakiasis
Larva Migrans

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11
Q

Tissue invading nematodes- tx

A

Albendazole

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12
Q

Trichinella Spiralis

A

Larvae is ingested from pork and other meet –> blood stream–> other organs esp skeletal muscle
Cuaes- myalgia, periorbital edema, and fever
may end up calcified

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13
Q

Aniskiasis-

A
Ingested from raw fish
sick within 48 hrs
feel a tickle in the throat
also causes- epigastric pain, nausea
Eosinophillic granulomas
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14
Q

Larva Migrans- Visceral

A

wheezing, CNS symptoms (eosinophilic menegoencephalitis), eosinophilia

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15
Q

Larva Migrans- Cutaneous

A

eosinophillic granuloma
tracts in skin
intense itching

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16
Q

Strongolyoides- is a major problem in what population

A

immunocompromised
kidney transplant recipients
HIV

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17
Q

Larva Migrans- what is going on with this

A

helminth invades wrong host, and doesn’t know what to do so it travels all over

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18
Q

Cestodes- tapeworm- tx

A

Praziquantel

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19
Q

Tanenia Solium

A

pigs are intermediate host

humans are the final host via eating encysted larvae

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20
Q

what happens if humans eat the Taenia solium eggs and not the larvae?

A

eggs hatch in smal intestine and migrate to form cystiecerci in the muscle and brain = cysticercosis

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21
Q

Cysticercosis

A

consequence of Taenia Solium eggs not larvae

seizures, obstructie hydrocephalus, eosinophilia

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22
Q

Cysticercosis- tx

A

Albendazole instead of praziqunetel

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23
Q

Taenia Sagniata- vector

A

Raw beef

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24
Q

Dihyloobothrium Latum- transmission

A

eat larvae of freshwater fish

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25
Dihyloobothrium latum- Sx
pernicious anemia
26
Echionococcus- vector
From Sheepdog
27
Enchinoccous- where does infect in the body
hydatid cysts in the liver
28
Enchinococcus- tx
surgical removal but have to be careful b/c can cause a lethal hypersensitivity rxn when Ag get into the blood
29
Cestodes
Taenia Solium Taenia Saginatum Diphyloobothrium Echinoccocus
30
Trematodes
Schistosoma | Paragonimiasis
31
Trematodes- tx
Prazaquintel
32
Schistosoma- transmission
water born in infected snails
33
Schistosoma- where does in live in body
mesenteric and portal vein
34
Schistosoma- causes
KATAYAMA FEVER cercarial dermatitis hepatosplenomegaly Eosinophilia
35
Paragonimiasis- transmission
fresh water crustaceans
36
Paragonimiasis- Sx
eosinophilic granulomas in the lung parenchyma
37
Paragonimiasis- what resemble
Tb
38
Protozoa- definition
free living single celled eukaryotes
39
Malaria- protozoal causes
Plasmodium falciparum Plasmodium. Vivax Plasmodium Ovale Plasmodium Malariae
40
Malaria tx
Chloroquine | Primaquine
41
Babesiosis- b. Microti, b. divergens- vector
ixodes scapularis tick (also caries lyme disease)
42
Babesiosis- b. microti, b. divergens- blood smear
Maltgese cross
43
Babesoides- b.microti, b.diverges- tx
quinine + clindamycin
44
Leishmaniasis- vector
sandfly bite
45
Leishmaniasis- appearance
Leishman Donovan bodies
46
Leishminiasis- tx
stibogluconate sodium or | pentamidine isethioiate
47
Trypanasoma brucei rhodesiense (more severe than) T.b. gambiense- dz
African sleeping sickness
48
Ssx of African sleeping sickness
skin ulcer that heals in 2 weeks fever,HA, arthralgias Winterbottoms sign (tender LAD on back of neck)
49
Tx of African Sleeping Sickness
Sumarin or pentamide | Melaarsoprol if CNS is involved
50
T.b Rhodensiense T.b. Gambiense- vector
Tse Tse fly
51
T. Cruzi- dz
Chagas dz
52
Chagas dz- Ssx
Chagoma Cardiac arrhythmia dilated cardiomyopathy toxic megacolon
53
Chagas dz- is MCC of what world wide
Heart failure
54
Chagas dz tx
nifurtimox or pentamide isethionate
55
T. Cruzi- vector
Reduviid bug- kissing bug | feeding on deficating person --> person scratches --> feces gets into chagoma--> transmit amastigotes
56
Entamoeba histolytica- Ssx
Blood diarrhea, hepatic avcesses, often asymptomatic | THIS IS THE ONLY PARASITE THAT EATS RBCS
57
Entamoeba histolytica- Tx
Metronidazole- especially in ther eare hepatic abcesses
58
Giardia lamblia- where does it live
mount spring water
59
Giardia lamlblia- motility?
yes.. it has a flagella
60
Giardia lamblia- Ssx
steatorrhea
61
Giardia lamblia-tx
furazolinode for peds | metronidazole
62
Trichimonas Vaginalis- Ssx
yellow/ Green frothy vaginal discharge itiching burning on urination
63
Trichimonias vaginalis- tx
metronidazole to pt and sexual partners
64
Protozoans found in AIDS pts
Toxoplasma Gondii Cryptosporidium PCP Isospora belli
65
Toxoplasma Gondii- Ssx
encephalitis, chorioretinitis, splenomegaly
66
T. Gondii- in pregnancy
pregnant women should avoid Cats | This is a ToRCH infection
67
T. Gondii tx
Sulfadiazine Pyrimethamine Folic Acid
68
T. Gondii- congenital infection
Choriorentinitis, hydrocephalus, and intracranial calcifications
69
Cryptosporidium- transmission
Swimming pools Eating fruit A problem in daycare centers
70
Cyrptosporidium- Ssx
watery diarrhea
71
Cryptosporidium- tx
Paramomycin for adults w/ HIV | Nitazoxanide for kids
72
PCP- Ssx
Interstial pneumonia | non productive cough
73
PCP- tx
TMP- SMX
74
Isospora belli- Ssx
Diarrhea | Eosinophilia
75
Isosopora belli- tx
TMP- SMX