HEENT Flashcards
Angioedema
Non-pitting edema of subcutaneous or submucosal tissues on lips, face, neck, extremities, larynx, gut
Hereditary angioedema cause
Mutation in C1-INH gene
Allergic angioedema pathophys
Histamine mediated.
More common
Non-allegic angioedema pathophys
Bradykinin-mediated
Less common
C1-INH deficiency
Can be caused by ACE-INH
Histamine-mediated angioedema clinical manifestatons
Urticaria
Flushing
Pruitus
Bronchospasm
ABD pain
Vomiting
Onset within 60 mins and could last 1-2 days
Bradykinin-mediated angioedema
No urticaria
More severe and longer duration
Usually within a week of exposure
Takes one day to peak and resolves in 2-3 days
Recurrent episodes
Angioedema physical exam focus
Head, neck. resp, abd
Monitor cardiac and O2 sat
Angioedeme diagnosis/lab
Good history
C4-INH level (cheaper)
C1-INH level
Tryptase if anaphylaxis
Laryngoscopy
Histamine mediated angiodema treatment
Epinephrine
Steroids
Histamine blockers (H1+H2)
Hereditary angioedema treatment
C1 esterase INH
ACE-INH induced angioedema treatment
Discontinue ACE-INH
Never use ACE-INH again
Aphthous Ulcer
Canker sours
Common
Aphthous ulcer cause
Stress
Human herpes virus 6
Can be in healthy
Aphthous ulcer clinical presentation
Painful
Recurrent
Localized, shallow, small, round, oval
Found on freely moving nonkeratinized oral mucous membrane
Yellow-gray fibrinid centers surrounded by red halos
Aphthous ulcer diagnosis
Biopsy to rule out squamous cell carcinoma.
If large rule out HIV, HSV, drug allergies, autoimmune
Aphthous ulcer management
Topical corticosteroid (triamcinolone acetonide)
Oral prednisone for severe
Cimetidine or thalidomide for recurrent
Glossitis
Inflammation of tongue
Glossitis cause
Anemia
Vitamin deficiency
Infections
Medication
Dehydrated
Oral thrush
Oral candidiasis albicans (yeast)
Common normal flora, but opportunistic pathogen.
Oral candidiasis risk factors
Diabetes mellitus
Broad Abx
Corticosteroids
Dentures
Oral candidiasis clinical presentation
Erythema
Painful creamy-white curd-like patches on tongue easily rubbed off with tongue blade.
Angular cheilitis
Oral candidiasis
Painful erythematous fissured patches in mouth
Can be sign of HIV
Seen in nutritional deficiencies
Oral candidiasis diagnosis
KOH
Spores and nonseptate mycelia
Biopsy
HIV
Oral candidiasis treatment
Fluconazole (antifungal)
0.12% chlorhexidine or H2O2 for relief
Nystatin powder on dentures