Heart Failure Flashcards
Heart failure is an impaired ability of the heart to either _______ or _______.
relax or pump blood
impaired LV contractile function is known clinically as…
systolic dysfunction
abnormal LV cardiac relaxation, stiffness or impaired filling is known clinically as…
diastolic dysfunction
T or F
Systolic dysfunction causes diastolic dysfunction.
F. one doesn’t cause the other
can systolic and diastolic dysfunction coexist?
yes
Generally, isolated right heart pathology suggests an issue with what system?
pulmonary
pulmonary hypertension can contribute to what type of cardiac dysfunction?
right ventricle
LHF, HFrEF is systolic or diastolic?
systolic
LHF HFpEF is systolic or diastolic?
diastolic
what does ejection fraction measure?
ability of ventricles to eject blood/ventricular function
The below factors have a positive impact on what factor of stroke volume? Preload, Afterload, Contractility or HR?
Increased venous return
increased filling time
increased ventricular compliance
increased filling pressure
increased preload
The below factors have a positive impact on what factor of stroke volume? Preload, Afterload, Contractility or HR?
increased peripheral vascular resistance
increased aortic pressure
decreased arterial wall compliance
increased afterload
The below factors have a positive impact on what factor of stroke volume? Preload, Afterload, Contractility or HR?
SNS stimulation leading to inotropy
increased contractility
The below factors have a positive impact on what factor of stroke volume? Preload, Afterload, Contractility or HR?
SNS stimulation leading to chronotropy
HR
Abrupt damage to myocardium can occur in what condition?
MI
What two factors cause gradual damage to the myocardium leading to HF?
Increased pressure
Increased volume
Progressive damage to myocardium causes what two changes to the heart?
cardiac remodeling
declining heart function
Decreased perfusion to the kidneys leads to what two physiologic changes which lead to CHF?
overactive RAAS system
SNS stimulation
The progression of heart disease can be visualized as a cycle. What are the steps of this cycle?
heart disease
LEADING TO
decreased CO
LEADING TO
neurohormonal stimulation
LEADING TO
vasoconstriction and sodium retention
LEADING TO
increased resistance and ventricular dilation
A pt. presents with the following findings. What type of HF do you suspect?
- clinical S/S of HF
- reduced LVEF (40% or less)
- increased LV ESV/EDV
HFrEF
HFrEF is also known as…
systolic heart failure
In HFrEF, _______ overload leads to ________ dilation and _________ remodeling
volume overload
chamber dilation
eccentric remodeling
HFrEF is caused by impaired contractility and high afterload. What conditions impair contractility and increase afterload?
Contractility: CAD, cardiomyopathy
Afterload: HTN
What is the normal range for LVEF?
50-55%
HFpEF is systolic or diastolic dysfunction?
Diastolic Dysfunction
Impaired LV relaxation and decreased LV compliance lead to…
diastolic dysfunction
What happens to the LVEF and EDV in HFpEF?
normal
When the LV increases its dependence on atrial contraction for filling, what results?
left atrial enlargement
HFrEF is a ______ overload, while HFpEF is a ________ overload
rEF: volume overload
pEF: pressure overload
what type of cardiac remodeling is seen in HFpEF?
concentric remodeling/hypertrophy
What risk factors do HFpEF and HFrEF have in common?
old age
HTN
CAD
DM
Patients with HFpEF compared to HFrEF tend to…
be older
have HTN
overweight
women
What is the most common cause of right heart failure?
LHF
The right heart is a low pressure, high compliance system, meaning it does not tolerate increases in ______
afterload
What conditions cause increased afterload in the right heart?
PE
chronic pulmonary disease
What is the MC cause of heart failure?
CAD
A patient with CAD presents with the following sxs. What should you immediately suspect?
dyspnea
fatigue/weakness
dependent edema
weight gain
nocturnal, nonproductive cough
nocturia
heart failure
What is the progression of dyspnea as heart failure worsens?
DOE
to
orthopnea
to
PND
to
dyspnea at rest
HF has many of the normal cardiovascular risk factors like CAD, PVD, DM, HTN, and obesity.
What endocrine disorders contribute to HF?
pheochromocytoma
thyroid abnormality
What is an early finding in decompensation in patients with HF?
S3/S4 gallop
What findings should you expect to see on cardiac physical exam of patients with HF?
elevated JVD
Displaced PMI
S3/S4 gallop
What findings should you expect to see on skin physical exam of patients with HF?
edema